Electron spin resonance spectroscopy studies on 15N-labeled and their deuterated nitroxyl spin probes used in molecular imaging

D. David Jebaraj, A. Milton Franklin Benial, Kazuhiro Ichikawa, Ken-Ichi Yamada, Hideo Utsumi

研究成果: 著書/レポートタイプへの貢献会議での発言

抄録

Electron Spin Resonance (ESR) studies were carried out for 2 mM concentration of 15N labeled carbamoyl-PROXYL, carboxy-PROXYL, MC-PROXYL and their deuterated derivatives using X-band ESR spectrometer. The ESR parameters such as linewidth, hyperfine coupling constant, g-factor, spin-spin relaxation time were determined. The lineshape analysis was also carried out. The observed linewidth values are ̃50% higher for undeuterated nitroxyl radicals compared with their deuterated derivatives. The lineshape analysis reveals that the observed ESR lineshape is a voigt lineshape, which is the convolution of a lorentzian and guassian profile. ESR lineshape analysis results that the lorentzian contribution is ̃20% higher for deuterated nitroxyl radicals compared with undeuterated nitroxyl radicals. The observed spin-spin relaxartion time for deuterated nitroxyl radicals is ̃50% longer compared with undeuterated nitroxyl radicals. The g value indicates the isotropic nature of nitroxyl radicals in pure water. From these results, the deuterated nitroxyl radicals are suitable spin probes for ESR/Overhauser- enhanced magnetic resonance (OMR) studies.

元の言語英語
ホスト出版物のタイトルProceeding of International Conference on Recent Trends in Applied Physics and Material Science, RAM 2013
ページ1171-1172
ページ数2
DOI
出版物ステータス出版済み - 7 18 2013
イベントInternational Conference on Recent Trends in Applied Physics and Material Science, RAM 2013 - Bikaner, Rajasthan, インド
継続期間: 2 1 20132 2 2013

出版物シリーズ

名前AIP Conference Proceedings
1536
ISSN(印刷物)0094-243X
ISSN(電子版)1551-7616

その他

その他International Conference on Recent Trends in Applied Physics and Material Science, RAM 2013
インド
Bikaner, Rajasthan
期間2/1/132/2/13

Fingerprint

electron paramagnetic resonance
probes
spectroscopy
superhigh frequencies
convolution integrals
magnetic resonance
relaxation time
spectrometers
profiles
water

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)

これを引用

Jebaraj, D. D., Benial, A. M. F., Ichikawa, K., Yamada, K-I., & Utsumi, H. (2013). Electron spin resonance spectroscopy studies on 15N-labeled and their deuterated nitroxyl spin probes used in molecular imaging. : Proceeding of International Conference on Recent Trends in Applied Physics and Material Science, RAM 2013 (pp. 1171-1172). (AIP Conference Proceedings; 巻数 1536). https://doi.org/10.1063/1.4810655

Electron spin resonance spectroscopy studies on 15N-labeled and their deuterated nitroxyl spin probes used in molecular imaging. / Jebaraj, D. David; Benial, A. Milton Franklin; Ichikawa, Kazuhiro; Yamada, Ken-Ichi; Utsumi, Hideo.

Proceeding of International Conference on Recent Trends in Applied Physics and Material Science, RAM 2013. 2013. p. 1171-1172 (AIP Conference Proceedings; 巻 1536).

研究成果: 著書/レポートタイプへの貢献会議での発言

Jebaraj, DD, Benial, AMF, Ichikawa, K, Yamada, K-I & Utsumi, H 2013, Electron spin resonance spectroscopy studies on 15N-labeled and their deuterated nitroxyl spin probes used in molecular imaging. : Proceeding of International Conference on Recent Trends in Applied Physics and Material Science, RAM 2013. AIP Conference Proceedings, 巻. 1536, pp. 1171-1172, International Conference on Recent Trends in Applied Physics and Material Science, RAM 2013, Bikaner, Rajasthan, インド, 2/1/13. https://doi.org/10.1063/1.4810655
Jebaraj DD, Benial AMF, Ichikawa K, Yamada K-I, Utsumi H. Electron spin resonance spectroscopy studies on 15N-labeled and their deuterated nitroxyl spin probes used in molecular imaging. : Proceeding of International Conference on Recent Trends in Applied Physics and Material Science, RAM 2013. 2013. p. 1171-1172. (AIP Conference Proceedings). https://doi.org/10.1063/1.4810655
Jebaraj, D. David ; Benial, A. Milton Franklin ; Ichikawa, Kazuhiro ; Yamada, Ken-Ichi ; Utsumi, Hideo. / Electron spin resonance spectroscopy studies on 15N-labeled and their deuterated nitroxyl spin probes used in molecular imaging. Proceeding of International Conference on Recent Trends in Applied Physics and Material Science, RAM 2013. 2013. pp. 1171-1172 (AIP Conference Proceedings).
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