Embedding of individual ferritin molecules in large, self-supporting silica nanofilms

Shigenori Fujikawa, Emi Muto, Toyoki Kunitake

研究成果: Contribution to journalArticle査読

12 被引用数 (Scopus)

抄録

We report herein the fabrication of ferritin-embedded self-supporting silica nanofilms via a simple spin-coating process. Ferritin was employed as a template molecule, and solutions of ferritin and silica were spread on a polymercoated silicon substrate, in this order, After dissolving the polymer underlayer by simply immersing ethanol, a centimeter-sized self-supporting nanofilm of ferritin/silica composite with a thickness of 15 nm was successfully transferred onto an alumina membrane without the film breaking. Ozone and hydrochloric acid solution treatment removed the template ferritin molecules from the composite film to produce corresponding transmembrane nanoholes. The reported method is very simple, and the fabrication of a protein-embedded self-supporting nanofilm enables the design of biomembranemimetic devices.

本文言語英語
ページ(範囲)4629-4633
ページ数5
ジャーナルLangmuir
23
8
DOI
出版ステータス出版済み - 4 10 2007
外部発表はい

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Condensed Matter Physics
  • Surfaces and Interfaces
  • Spectroscopy
  • Electrochemistry

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