Empathizing associates with mean diffusivity

Hikaru Takeuchi, Yasuyuki Taki, Rui Nouchi, Ryoichi Yokoyama, Yuka Kotozaki, Seishu Nakagawa, Atsushi Sekiguchi, Kunio Iizuka, Yuki Yamamoto, Sugiko Hanawa, Tsuyoshi Araki, Carlos Makoto Miyauchi, Kohei Sakaki, Yuko Sassa, Takayuki Nozawa, Shigeyuki Ikeda, Susumu Yokota, Magistro Daniele, Ryuta Kawashima

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

抄録

Empathizing is defined as “the drive to identify another’s mental states and to respond to these with an appropriate emotion” and systemizing is defined as “the drive to the drive to analyze and construct rule-based systems”. While mean diffusivity (MD) has been robustly associated with several cognitive traits and disorders related with empathizing and systemizing, its direct correlation with empathizing and systemizing remains to be investigated. We undertook voxel-by-voxel investigations of regional MD to discover microstructural correlates of empathizing, systemizing, and the discrepancy between them (D score: systemizing − empathizing). Whole-brain analyses of covariance revealed that across both sexes, empathizing was positively correlated with MD of (a) an anatomical cluster that primarily spreads in the areas in and adjacent to the left dorsolateral prefrontal cortex, left anterior to the middle cingulate cortex, and left insula and (b) an anatomical cluster of the left postcentral gyrus and left rolandic operculum. The former overlaps with positive MD correlates of cooperativeness. The D score and systemizing did not show significant correlations. In conclusion, while increased MD has generally been associated with reduced neural tissues and possibly area function, higher empathizing and cooperativeness were commonly reflected by greater MD values in areas (a) that mainly overlap with areas that play a key role in emotional salience and empathy. In addition, higher empathizing was correlated with greater MD values in areas (b) that play a key role in the mirror neuron system.

元の言語英語
記事番号8856
ジャーナルScientific reports
9
発行部数1
DOI
出版物ステータス出版済み - 12 1 2019
外部発表Yes

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Mirror Neurons
Somatosensory Cortex
Gyrus Cinguli
Prefrontal Cortex
Emotions
Brain
Drive

All Science Journal Classification (ASJC) codes

  • General

これを引用

Takeuchi, H., Taki, Y., Nouchi, R., Yokoyama, R., Kotozaki, Y., Nakagawa, S., ... Kawashima, R. (2019). Empathizing associates with mean diffusivity. Scientific reports, 9(1), [8856]. https://doi.org/10.1038/s41598-019-45106-1

Empathizing associates with mean diffusivity. / Takeuchi, Hikaru; Taki, Yasuyuki; Nouchi, Rui; Yokoyama, Ryoichi; Kotozaki, Yuka; Nakagawa, Seishu; Sekiguchi, Atsushi; Iizuka, Kunio; Yamamoto, Yuki; Hanawa, Sugiko; Araki, Tsuyoshi; Miyauchi, Carlos Makoto; Sakaki, Kohei; Sassa, Yuko; Nozawa, Takayuki; Ikeda, Shigeyuki; Yokota, Susumu; Daniele, Magistro; Kawashima, Ryuta.

:: Scientific reports, 巻 9, 番号 1, 8856, 01.12.2019.

研究成果: ジャーナルへの寄稿記事

Takeuchi, H, Taki, Y, Nouchi, R, Yokoyama, R, Kotozaki, Y, Nakagawa, S, Sekiguchi, A, Iizuka, K, Yamamoto, Y, Hanawa, S, Araki, T, Miyauchi, CM, Sakaki, K, Sassa, Y, Nozawa, T, Ikeda, S, Yokota, S, Daniele, M & Kawashima, R 2019, 'Empathizing associates with mean diffusivity', Scientific reports, 巻. 9, 番号 1, 8856. https://doi.org/10.1038/s41598-019-45106-1
Takeuchi H, Taki Y, Nouchi R, Yokoyama R, Kotozaki Y, Nakagawa S その他. Empathizing associates with mean diffusivity. Scientific reports. 2019 12 1;9(1). 8856. https://doi.org/10.1038/s41598-019-45106-1
Takeuchi, Hikaru ; Taki, Yasuyuki ; Nouchi, Rui ; Yokoyama, Ryoichi ; Kotozaki, Yuka ; Nakagawa, Seishu ; Sekiguchi, Atsushi ; Iizuka, Kunio ; Yamamoto, Yuki ; Hanawa, Sugiko ; Araki, Tsuyoshi ; Miyauchi, Carlos Makoto ; Sakaki, Kohei ; Sassa, Yuko ; Nozawa, Takayuki ; Ikeda, Shigeyuki ; Yokota, Susumu ; Daniele, Magistro ; Kawashima, Ryuta. / Empathizing associates with mean diffusivity. :: Scientific reports. 2019 ; 巻 9, 番号 1.
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author = "Hikaru Takeuchi and Yasuyuki Taki and Rui Nouchi and Ryoichi Yokoyama and Yuka Kotozaki and Seishu Nakagawa and Atsushi Sekiguchi and Kunio Iizuka and Yuki Yamamoto and Sugiko Hanawa and Tsuyoshi Araki and Miyauchi, {Carlos Makoto} and Kohei Sakaki and Yuko Sassa and Takayuki Nozawa and Shigeyuki Ikeda and Susumu Yokota and Magistro Daniele and Ryuta Kawashima",
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AU - Takeuchi, Hikaru

AU - Taki, Yasuyuki

AU - Nouchi, Rui

AU - Yokoyama, Ryoichi

AU - Kotozaki, Yuka

AU - Nakagawa, Seishu

AU - Sekiguchi, Atsushi

AU - Iizuka, Kunio

AU - Yamamoto, Yuki

AU - Hanawa, Sugiko

AU - Araki, Tsuyoshi

AU - Miyauchi, Carlos Makoto

AU - Sakaki, Kohei

AU - Sassa, Yuko

AU - Nozawa, Takayuki

AU - Ikeda, Shigeyuki

AU - Yokota, Susumu

AU - Daniele, Magistro

AU - Kawashima, Ryuta

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