Enantiodivergent total syntheses of nanaomycins and their enantiomers, kalafungins

Kuniaki Tatsuta, Kohji Akimoto, Masahiko Annaka, Yutaka Ohno, Mitsuhiro Kinoshita

研究成果: ジャーナルへの寄稿記事

92 引用 (Scopus)

抄録

The first, enantiospecific total syntheses of pyranonaphthoquinone antibiotics, nanaomycins D and A, and their enantiomers, kalafungin and 4-deoxykalafunginic acid are described by an "enantiodivergent" strategy from a common optically active intermediate, (lS,3RS,4S)-3,4-dihydro-5,9,10-trimethoxy-l-methyl-lH-naphtho[2,3-c]pyran-3,4-diol, which has been derived from L-rhamnose via condensation of 4-methoxy-3-(phenylsulfonyl)-l(3//)-isobenzofuranone and methyl 3,4,6-trideoxy-a-L-g/ylero-hex-3-enopyranosid-2-ulose.

元の言語英語
ページ(範囲)1699-1706
ページ数8
ジャーナルBulletin of the Chemical Society of Japan
58
発行部数6
DOI
出版物ステータス出版済み - 1 1 1985
外部発表Yes

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Enantiomers
Pyrans
Rhamnose
Condensation
Anti-Bacterial Agents
Acids
kalafungin
nanaomycin A

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

これを引用

Enantiodivergent total syntheses of nanaomycins and their enantiomers, kalafungins. / Tatsuta, Kuniaki; Akimoto, Kohji; Annaka, Masahiko; Ohno, Yutaka; Kinoshita, Mitsuhiro.

:: Bulletin of the Chemical Society of Japan, 巻 58, 番号 6, 01.01.1985, p. 1699-1706.

研究成果: ジャーナルへの寄稿記事

Tatsuta, Kuniaki ; Akimoto, Kohji ; Annaka, Masahiko ; Ohno, Yutaka ; Kinoshita, Mitsuhiro. / Enantiodivergent total syntheses of nanaomycins and their enantiomers, kalafungins. :: Bulletin of the Chemical Society of Japan. 1985 ; 巻 58, 番号 6. pp. 1699-1706.
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