Enantioselective Alkylation by Binaphthyl Chiral phase-transfer catalysts: A DFT-based conformational analysis

Takashi Kamachi, Kazunari Yoshizawa

研究成果: ジャーナルへの寄稿記事

17 引用 (Scopus)

抄録

A conformational search method based on the density functional theory (DFT) was successfully applied to explore a mechanism for the highly enantioselective alkylation by binaphthyl-modifed chiral phase-transfer catalysts. Key interactions that govern the enantioselectivity were analyzed. The computational results are encouraging for further application of the DFT-based conformational search toward the rational design of next-generation asymmetric phase transfer catalysts.

元の言語英語
ページ(範囲)472-475
ページ数4
ジャーナルOrganic Letters
16
発行部数2
DOI
出版物ステータス出版済み - 3 17 2014

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alkylation
Alkylation
Density functional theory
density functional theory
catalysts
Catalysts
Enantioselectivity
interactions

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

これを引用

Enantioselective Alkylation by Binaphthyl Chiral phase-transfer catalysts : A DFT-based conformational analysis. / Kamachi, Takashi; Yoshizawa, Kazunari.

:: Organic Letters, 巻 16, 番号 2, 17.03.2014, p. 472-475.

研究成果: ジャーナルへの寄稿記事

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