Endometrial metaplasia associated with endometrial carcinoma

Tsunehisa Kaku, Naoki Tsukamoto, Nobuhiro Tsuruchi, Kouichiro Sugihara, Toshiharu Kamura, Hitoo Nakano

研究成果: ジャーナルへの寄稿記事

31 引用 (Scopus)


To clarify the relationship of metaplasia to endometrial carcinoma.Methods: Between 1984-1990, 73 cases of stage I-II endometrial carcinoma treated initially by hysterectomy were reviewed histologically. The metaplasias were classified as squamous, syncytial papillary, ciliated-cell, eosinophilic, mucinous, dear-cell, or hobnail. We assessed the histologic type and grade of the carcinoma, depth of myometrial invasion, presence or absence of lymph-vascular space invasion, and presence or absence of lymph node metastases.Results: Forty of 73 patients (55%) had one or more areas of metaplasia in the endometrium adjacent to the carcinoma. Ciliated-cell metaplasia (28 of 73; 38%) was the most common type encountered. Women with both endometrial carcinoma and metaplasia were significantly younger than those with carcinoma without metaplasia (P < .05). Compared with carcinomas without metaplasia, those with metaplasia were well differentiated (P < .01) and lacked myometrial invasion (P < .01) and pelvic lymph node metastases (P < .05). The presence of metaplasia was also significantly correlated with the presence of endometrial hyperplasia (P < .01).Conclusion: In endometrial carcinomas, the presence of endometrial metaplasia suggests a favorable prognosis.

ジャーナルObstetrics and Gynecology
出版物ステータス出版済み - 11 1992

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynaecology

フィンガープリント Endometrial metaplasia associated with endometrial carcinoma' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

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    Kaku, T., Tsukamoto, N., Tsuruchi, N., Sugihara, K., Kamura, T., & Nakano, H. (1992). Endometrial metaplasia associated with endometrial carcinoma. Obstetrics and Gynecology, 80(5), 812-816.