抄録
We fabricated a scaffold of poly (lactic acid) and acidic gelatin, a sustained-release carrier of basic fibroblast growth factor (bFGF), which is a positive regulator of angiogenesis. After 1 week of implantation into mesentery of rats, blood vessels induced in the bFGF-containing scaffolds were almost double those in the bFGF-free scaffolds. Further, histological examination of hepatocyte-immobilizing scaffolds retrieved after 1 week of implantation into the mesentery of the rats that received a 70% hepatectomy revealed that the bFGF-containing scaffolds were more efficient for immobilized cell survival than the bFGF-free scaffolds. As well, hepatocytes in the bFGF-containing scaffolds kept their hepatospecific glycogen storage capacity.
本文言語 | 英語 |
---|---|
ページ(範囲) | 913-917 |
ページ数 | 5 |
ジャーナル | JOURNAL OF CHEMICAL ENGINEERING OF JAPAN |
巻 | 38 |
号 | 11 |
DOI | |
出版ステータス | 出版済み - 11月 20 2005 |
!!!All Science Journal Classification (ASJC) codes
- 化学 (全般)
- 化学工学(全般)