Enhancement of octacalcium phosphate deposition on a titanium surface activated by electron cyclotron resonance plasma oxidation

Yusuke Orii, Hiroshi Masumoto, Yoshitomo Honda, Takahisa Anada, Takashi Goto, Keiichi Sasaki, Osamu Suzuki

研究成果: ジャーナルへの寄稿記事

7 引用 (Scopus)

抄録

The present study was designed to investigate whether the formation of octacalcium phosphate (OCP) is accelerated on titanium (Ti) surface by an electron cyclotron resonance (ECR) plasma oxidation at various pressures and temperatures. X-ray diffraction (XRD) of Ti-oxidized substrates showed that the rutile TiO2 phase on its surfaces appeared at 300°C and was crystallized when the oxidation temperature increased up to 600°C. The thickness of TiO2 film on the substrates increased progressively as the temperature increased. The oxidized Ti surfaces were soaked in calcium and phosphate solutions supersaturated with respect to both hydroxyapatite (HA) and OCP but slightly supersaturated with dicalcium phosphate dihydrate (DCPD). OCP crystals with a blade-like morphology were deposited as the primary crystalline phase on Ti substrates, while DCPD was included as a minor constituent. The amount of OCP deposition was maximized under 0.015 Pa in 300°C. On the other hand, the oxidation temperature did not show a significant effect on the deposit in the range examined. The phase conversion from OCP to HA, determined by XRD, was demonstrated to occur even at 1 day and to advance until 7 days by immersing the Ti substrate with the deposit in simulated body fluid at 37°C. The present results suggest that ECR plasma oxidation could be used to improve a Ti surface regarding its bioactivity due to the enhancement of osteoconductive OCP deposition.

元の言語英語
ページ(範囲)476-483
ページ数8
ジャーナルJournal of Biomedical Materials Research - Part B Applied Biomaterials
93
発行部数2
DOI
出版物ステータス出版済み - 5 1 2010
外部発表Yes

Fingerprint

Electron cyclotron resonance
Titanium
Phosphates
Plasmas
Oxidation
Substrates
Durapatite
Deposits
Hydroxyapatite
X ray diffraction
Temperature
Body fluids
Bioactivity
octacalcium phosphate
Crystalline materials
Crystals
Calcium

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Biomaterials

これを引用

Enhancement of octacalcium phosphate deposition on a titanium surface activated by electron cyclotron resonance plasma oxidation. / Orii, Yusuke; Masumoto, Hiroshi; Honda, Yoshitomo; Anada, Takahisa; Goto, Takashi; Sasaki, Keiichi; Suzuki, Osamu.

:: Journal of Biomedical Materials Research - Part B Applied Biomaterials, 巻 93, 番号 2, 01.05.2010, p. 476-483.

研究成果: ジャーナルへの寄稿記事

Orii, Yusuke ; Masumoto, Hiroshi ; Honda, Yoshitomo ; Anada, Takahisa ; Goto, Takashi ; Sasaki, Keiichi ; Suzuki, Osamu. / Enhancement of octacalcium phosphate deposition on a titanium surface activated by electron cyclotron resonance plasma oxidation. :: Journal of Biomedical Materials Research - Part B Applied Biomaterials. 2010 ; 巻 93, 番号 2. pp. 476-483.
@article{f737c409c968418aaaa763c06d6ab48d,
title = "Enhancement of octacalcium phosphate deposition on a titanium surface activated by electron cyclotron resonance plasma oxidation",
abstract = "The present study was designed to investigate whether the formation of octacalcium phosphate (OCP) is accelerated on titanium (Ti) surface by an electron cyclotron resonance (ECR) plasma oxidation at various pressures and temperatures. X-ray diffraction (XRD) of Ti-oxidized substrates showed that the rutile TiO2 phase on its surfaces appeared at 300°C and was crystallized when the oxidation temperature increased up to 600°C. The thickness of TiO2 film on the substrates increased progressively as the temperature increased. The oxidized Ti surfaces were soaked in calcium and phosphate solutions supersaturated with respect to both hydroxyapatite (HA) and OCP but slightly supersaturated with dicalcium phosphate dihydrate (DCPD). OCP crystals with a blade-like morphology were deposited as the primary crystalline phase on Ti substrates, while DCPD was included as a minor constituent. The amount of OCP deposition was maximized under 0.015 Pa in 300°C. On the other hand, the oxidation temperature did not show a significant effect on the deposit in the range examined. The phase conversion from OCP to HA, determined by XRD, was demonstrated to occur even at 1 day and to advance until 7 days by immersing the Ti substrate with the deposit in simulated body fluid at 37°C. The present results suggest that ECR plasma oxidation could be used to improve a Ti surface regarding its bioactivity due to the enhancement of osteoconductive OCP deposition.",
author = "Yusuke Orii and Hiroshi Masumoto and Yoshitomo Honda and Takahisa Anada and Takashi Goto and Keiichi Sasaki and Osamu Suzuki",
year = "2010",
month = "5",
day = "1",
doi = "10.1002/jbm.b.31605",
language = "English",
volume = "93",
pages = "476--483",
journal = "Journal of Biomedical Materials Research",
issn = "1552-4973",
publisher = "Heterocorporation",
number = "2",

}

TY - JOUR

T1 - Enhancement of octacalcium phosphate deposition on a titanium surface activated by electron cyclotron resonance plasma oxidation

AU - Orii, Yusuke

AU - Masumoto, Hiroshi

AU - Honda, Yoshitomo

AU - Anada, Takahisa

AU - Goto, Takashi

AU - Sasaki, Keiichi

AU - Suzuki, Osamu

PY - 2010/5/1

Y1 - 2010/5/1

N2 - The present study was designed to investigate whether the formation of octacalcium phosphate (OCP) is accelerated on titanium (Ti) surface by an electron cyclotron resonance (ECR) plasma oxidation at various pressures and temperatures. X-ray diffraction (XRD) of Ti-oxidized substrates showed that the rutile TiO2 phase on its surfaces appeared at 300°C and was crystallized when the oxidation temperature increased up to 600°C. The thickness of TiO2 film on the substrates increased progressively as the temperature increased. The oxidized Ti surfaces were soaked in calcium and phosphate solutions supersaturated with respect to both hydroxyapatite (HA) and OCP but slightly supersaturated with dicalcium phosphate dihydrate (DCPD). OCP crystals with a blade-like morphology were deposited as the primary crystalline phase on Ti substrates, while DCPD was included as a minor constituent. The amount of OCP deposition was maximized under 0.015 Pa in 300°C. On the other hand, the oxidation temperature did not show a significant effect on the deposit in the range examined. The phase conversion from OCP to HA, determined by XRD, was demonstrated to occur even at 1 day and to advance until 7 days by immersing the Ti substrate with the deposit in simulated body fluid at 37°C. The present results suggest that ECR plasma oxidation could be used to improve a Ti surface regarding its bioactivity due to the enhancement of osteoconductive OCP deposition.

AB - The present study was designed to investigate whether the formation of octacalcium phosphate (OCP) is accelerated on titanium (Ti) surface by an electron cyclotron resonance (ECR) plasma oxidation at various pressures and temperatures. X-ray diffraction (XRD) of Ti-oxidized substrates showed that the rutile TiO2 phase on its surfaces appeared at 300°C and was crystallized when the oxidation temperature increased up to 600°C. The thickness of TiO2 film on the substrates increased progressively as the temperature increased. The oxidized Ti surfaces were soaked in calcium and phosphate solutions supersaturated with respect to both hydroxyapatite (HA) and OCP but slightly supersaturated with dicalcium phosphate dihydrate (DCPD). OCP crystals with a blade-like morphology were deposited as the primary crystalline phase on Ti substrates, while DCPD was included as a minor constituent. The amount of OCP deposition was maximized under 0.015 Pa in 300°C. On the other hand, the oxidation temperature did not show a significant effect on the deposit in the range examined. The phase conversion from OCP to HA, determined by XRD, was demonstrated to occur even at 1 day and to advance until 7 days by immersing the Ti substrate with the deposit in simulated body fluid at 37°C. The present results suggest that ECR plasma oxidation could be used to improve a Ti surface regarding its bioactivity due to the enhancement of osteoconductive OCP deposition.

UR - http://www.scopus.com/inward/record.url?scp=77951160158&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77951160158&partnerID=8YFLogxK

U2 - 10.1002/jbm.b.31605

DO - 10.1002/jbm.b.31605

M3 - Article

C2 - 20166123

AN - SCOPUS:77951160158

VL - 93

SP - 476

EP - 483

JO - Journal of Biomedical Materials Research

JF - Journal of Biomedical Materials Research

SN - 1552-4973

IS - 2

ER -