Enhancement of saccharothriolide production and discovery of a new metabolite, saccharothriolide C 2 , by combined-culture of Saccharothrix sp. and Tsukamurella pulmonis

Yulu Jiang, Shan Lu, Go Hirai, Taira Kato, Hiroyasu Onaka, Hideaki Kakeya

研究成果: ジャーナルへの寄稿記事

抄録

A combined-culture method was applied to saccharothriolide-producing strain Saccharothrix sp. A1506 with the mycolic acid-containing bacterium (MACB) Tsukamurella pulmonis TP-B0596. The combined-culture not only enhanced saccharothriolide production, but also produced saccharothriolide C 2 , a new C-2 epimer of saccharothriolide C, thereby indicating its potential for increasing the chemical diversity of microbial metabolites.

元の言語英語
ページ(範囲)1072-1074
ページ数3
ジャーナルTetrahedron Letters
60
発行部数15
DOI
出版物ステータス出版済み - 4 11 2019

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Mycolic Acids
Metabolites
Bacteria

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

これを引用

Enhancement of saccharothriolide production and discovery of a new metabolite, saccharothriolide C 2 , by combined-culture of Saccharothrix sp. and Tsukamurella pulmonis . / Jiang, Yulu; Lu, Shan; Hirai, Go; Kato, Taira; Onaka, Hiroyasu; Kakeya, Hideaki.

:: Tetrahedron Letters, 巻 60, 番号 15, 11.04.2019, p. 1072-1074.

研究成果: ジャーナルへの寄稿記事

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abstract = "A combined-culture method was applied to saccharothriolide-producing strain Saccharothrix sp. A1506 with the mycolic acid-containing bacterium (MACB) Tsukamurella pulmonis TP-B0596. The combined-culture not only enhanced saccharothriolide production, but also produced saccharothriolide C 2 , a new C-2 epimer of saccharothriolide C, thereby indicating its potential for increasing the chemical diversity of microbial metabolites.",
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AU - Kakeya, Hideaki

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