Tidal responses to El Niño–Southern Oscillation (ENSO) in the mesosphere and lower thermosphere (MLT) are investigated for the first time using reanalysis data-driven simulations covering 21 years. The simulation is carried out with the Ground-to-topside Atmosphere-Ionosphere model for Aeronomy (GAIA) during 1996–2016, which covers nine ENSO events. ENSO impacts on diurnal tides at 100 km altitude are analyzed and cross-compared among temperature (T), zonal wind (U), and meridional wind (V), which reveals the following salient features: (1) Tidal response can differ significantly among T, U, and V in terms of magnitude and latitudinal structure, making detection of ENSO effects sensitive to the parameter used and the location of a ground station; (2) the nonmigrating DE3 tide in T and U shows a prominent hemisphere asymmetric response to La Niña, with an increase between 0° and 30°N and a decrease between 30° and 0°S. In contrast, DE3 in V exhibits no significant response; (3) the migrating DW1 enhances during El Niño in equatorial regions for T and U but in off-equatorial regions for V. As the first ENSO study based on reanalysis-driven simulations, GAIA's full set of tidal responses in T, U, and V provides us with a necessary global context to better understand and cross-compare observations during ENSO events. Comparisons with observations during the 1997–98 El Niño and 2010–11 La Niña reveal good agreement in both magnitude and timing. Comparisons with “free-run” WACCM simulations (T) show consistent results in nonmigrating tides DE2 and DE3 but differences in the migrating DW1 tide.
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