Enteric nervous system and endocrine cells demonstrated in the gut in teratomas

Ryuichiro Hirose, Tomoaki Taguchi, Sachiyo Suita, Osami Nada

研究成果: Contribution to journalArticle査読

抄録

A case of retroperitoneal teratoma, showing considerable morphological development presented as an encapsulated and pedunculated tumour with a seemingly mature intestinal loop. Markedly complex intramural nerve plexuses and numerous epithelial endocrine cells were revealed immunohistochemically in the gut tissue. Ten other mature teratomas containing gastrointestinal tissues were examined for comparison, but neither intramural ganglia nor nervous networks were found in the gut components, despite the presence of amine- and/or peptide-containing endocrine cells in all intestinal mucosa linings. Enteric endocrine cells were found to occur irrespective of the differentiation of intestinal layers or the occurrence of neural elements. These findings suggest that the epithelial endocrine cells of intestinal mucosa do not have the same origin as enteric neurons, but are rather of endodermal origin. This invertebrate well-formed teratoma, containing a highly organized enteric nervous system, suggests that teratoma and fetus in fetu are related entities distinguished by the presence of a vertebral axis.

本文言語英語
ページ(範囲)499-506
ページ数8
ジャーナルVirchows Archiv A Pathological Anatomy and Histopathology
422
6
DOI
出版ステータス出版済み - 11 1 1993

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine

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