TY - JOUR
T1 - Entomological assessment of the status and risk of mosquito-borne arboviral transmission in Ghana
AU - Amoa-Bosompem, Michael
AU - Kobayashi, Daisuke
AU - Murota, Katsunori
AU - Faizah, Astri Nur
AU - Itokawa, Kentaro
AU - Fujita, Ryosuke
AU - Osei, Joseph Harold Nyarko
AU - Agbosu, Esinam
AU - Pratt, Deborah
AU - Kimura, Shohei
AU - Kwofie, Kofi Dadzie
AU - Ohashi, Mitsuko
AU - Bonney, Joseph H.Kofi
AU - Dadzie, Samuel
AU - Sasaki, Toshinori
AU - Ohta, Nobuo
AU - Isawa, Haruhiko
AU - Sawabe, Kyoko
AU - Iwanaga, Shiroh
N1 - Funding Information:
Funding: This study was funded by the Japan Initiative for Global Research Network on Infectious Diseases (J-GRID) and the Research Program on Emerging and Re-emerging Infectious Diseases from the Japan Agency for Medical Research and Development (AMED). This study was supported by JSPS KAKENHI Grant Numbers JP16J09470, JP15H04614, JP18K19220, and JP18H02856.
Publisher Copyright:
© 2020 by the authors.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020
Y1 - 2020
N2 - Entomological surveillance is one of the tools used in monitoring and controlling vectorborne diseases. However, the use of entomological surveillance for arboviral infection vector control is often dependent on finding infected individuals. Although this method may suffice in highly endemic areas, it is not as effective in controlling the spread of diseases in low endemic and nonendemic areas. In this study, we examined the efficiency of using entomological markers to assess the status and risk of arbovirus infection in Ghana, which is considered a non-endemic country, by combining mosquito surveillance with virus isolation and detection. This study reports the presence of cryptic species of mosquitoes in Ghana, demonstrating the need to combine morphological identification and molecular techniques in mosquito surveillance. Furthermore, although no medically important viruses were detected, the importance of insect-specific viruses in understanding virus evolution and arbovirus transmission is discussed. This study reports the first mutualistic relationship between dengue virus and the double-stranded RNA Aedes aegypti totivirus. Finally, this study discusses the complexity of the virome of Aedes and Culex mosquitoes and its implication for arbovirus transmission.
AB - Entomological surveillance is one of the tools used in monitoring and controlling vectorborne diseases. However, the use of entomological surveillance for arboviral infection vector control is often dependent on finding infected individuals. Although this method may suffice in highly endemic areas, it is not as effective in controlling the spread of diseases in low endemic and nonendemic areas. In this study, we examined the efficiency of using entomological markers to assess the status and risk of arbovirus infection in Ghana, which is considered a non-endemic country, by combining mosquito surveillance with virus isolation and detection. This study reports the presence of cryptic species of mosquitoes in Ghana, demonstrating the need to combine morphological identification and molecular techniques in mosquito surveillance. Furthermore, although no medically important viruses were detected, the importance of insect-specific viruses in understanding virus evolution and arbovirus transmission is discussed. This study reports the first mutualistic relationship between dengue virus and the double-stranded RNA Aedes aegypti totivirus. Finally, this study discusses the complexity of the virome of Aedes and Culex mosquitoes and its implication for arbovirus transmission.
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U2 - 10.3390/v12020147
DO - 10.3390/v12020147
M3 - Article
C2 - 32012771
AN - SCOPUS:85078765767
VL - 12
JO - Viruses
JF - Viruses
SN - 1999-4915
IS - 2
M1 - v12020147
ER -