Enzymatic synthesis of sugar amino acid esters in organic solvents

Tatsuo Maruyama, Shin Ichiro Nagasawa, Masahiro Goto

    研究成果: Contribution to journalArticle査読

    24 被引用数 (Scopus)

    抄録

    The enzymatic synthesis of sugar amino acid esters in polar organic solvents was studied using surfactant-enzyme complexes, which were previously developed as a highly active biocatalyst in organic solvents. Of the several lipases and proteases tested, the surfactant-subtilisin complex exhibited the highest synthetic activity in pyridine. The amino acid was regioselectively introduced at the C-6 position of D-glucose and at the C-6' of maltose by the surfactant-subtilisin complex. This biocatalyst was found to effectively catalyze the synthesis of various sugar amino acid esters in a polar organic solvent.

    本文言語英語
    ページ(範囲)357-361
    ページ数5
    ジャーナルJournal of Bioscience and Bioengineering
    94
    4
    DOI
    出版ステータス出版済み - 2002

    All Science Journal Classification (ASJC) codes

    • バイオテクノロジー
    • バイオエンジニアリング
    • 応用微生物学とバイオテクノロジー

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