Ependyma-lined canal with surrounding neuroglial tissues in lumbosacral lipomatous malformations: Relationship with retained medullary cord

Nobuya Murakami, Takato Morioka, Takafumi Shimogawa, Nobutaka Mukae, Satoshi Inoha, Takakazu Sasaguri, Satoshi Suzuki, Koji Iihara

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

抄録

Background: An ependyma-lined canal with surrounding neuroglial tissues can be present in lumbosacral lipomatous malformations; however, the precise embryological significance is still unclear. Method: Six out of 50 patients with lipomatous malformations had ependymal structures. We retrospectively analyzed the clinical, neuroradiological, and histological findings of these patients to demonstrate the relationship with the embryological background of the retained medullary cord (RMC), which normally regresses, but was retained here because of late arrest of secondary neurulation. Results: Five (13.9%) of 36 patients with filar and caudal types and 1 of 3 lipomyelomeningoceles had ependymal structures, while none with dorsal and transitional types had these tissues. Histologically, the ependymal structures surrounded by neuroglial tissue and containing various amounts of adipose tissue bear a striking resemblance to the ependymal structures in RMC. Conclusion: The 13.9% incidence of association between the ependymal structures and filar and caudal types is thought to be because of second ary neurulation failure with the same embryological background as that of RMC. Dorsal and transitional types, resulting from primary neurulation failure, therefore, did not have ependymal structures.

元の言語英語
ページ(範囲)387-394
ページ数8
ジャーナルPediatric Neurosurgery
53
発行部数6
DOI
出版物ステータス出版済み - 12 1 2018

Fingerprint

Neurulation
Ependyma
Adipose Tissue
Incidence

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Surgery
  • Clinical Neurology

これを引用

Ependyma-lined canal with surrounding neuroglial tissues in lumbosacral lipomatous malformations : Relationship with retained medullary cord. / Murakami, Nobuya; Morioka, Takato; Shimogawa, Takafumi; Mukae, Nobutaka; Inoha, Satoshi; Sasaguri, Takakazu; Suzuki, Satoshi; Iihara, Koji.

:: Pediatric Neurosurgery, 巻 53, 番号 6, 01.12.2018, p. 387-394.

研究成果: ジャーナルへの寄稿記事

@article{520f7cdc0149459a8684c40ecb2140fb,
title = "Ependyma-lined canal with surrounding neuroglial tissues in lumbosacral lipomatous malformations: Relationship with retained medullary cord",
abstract = "Background: An ependyma-lined canal with surrounding neuroglial tissues can be present in lumbosacral lipomatous malformations; however, the precise embryological significance is still unclear. Method: Six out of 50 patients with lipomatous malformations had ependymal structures. We retrospectively analyzed the clinical, neuroradiological, and histological findings of these patients to demonstrate the relationship with the embryological background of the retained medullary cord (RMC), which normally regresses, but was retained here because of late arrest of secondary neurulation. Results: Five (13.9{\%}) of 36 patients with filar and caudal types and 1 of 3 lipomyelomeningoceles had ependymal structures, while none with dorsal and transitional types had these tissues. Histologically, the ependymal structures surrounded by neuroglial tissue and containing various amounts of adipose tissue bear a striking resemblance to the ependymal structures in RMC. Conclusion: The 13.9{\%} incidence of association between the ependymal structures and filar and caudal types is thought to be because of second ary neurulation failure with the same embryological background as that of RMC. Dorsal and transitional types, resulting from primary neurulation failure, therefore, did not have ependymal structures.",
author = "Nobuya Murakami and Takato Morioka and Takafumi Shimogawa and Nobutaka Mukae and Satoshi Inoha and Takakazu Sasaguri and Satoshi Suzuki and Koji Iihara",
year = "2018",
month = "12",
day = "1",
doi = "10.1159/000494029",
language = "English",
volume = "53",
pages = "387--394",
journal = "Pediatric Neurosurgery",
issn = "1016-2291",
publisher = "S. Karger AG",
number = "6",

}

TY - JOUR

T1 - Ependyma-lined canal with surrounding neuroglial tissues in lumbosacral lipomatous malformations

T2 - Relationship with retained medullary cord

AU - Murakami, Nobuya

AU - Morioka, Takato

AU - Shimogawa, Takafumi

AU - Mukae, Nobutaka

AU - Inoha, Satoshi

AU - Sasaguri, Takakazu

AU - Suzuki, Satoshi

AU - Iihara, Koji

PY - 2018/12/1

Y1 - 2018/12/1

N2 - Background: An ependyma-lined canal with surrounding neuroglial tissues can be present in lumbosacral lipomatous malformations; however, the precise embryological significance is still unclear. Method: Six out of 50 patients with lipomatous malformations had ependymal structures. We retrospectively analyzed the clinical, neuroradiological, and histological findings of these patients to demonstrate the relationship with the embryological background of the retained medullary cord (RMC), which normally regresses, but was retained here because of late arrest of secondary neurulation. Results: Five (13.9%) of 36 patients with filar and caudal types and 1 of 3 lipomyelomeningoceles had ependymal structures, while none with dorsal and transitional types had these tissues. Histologically, the ependymal structures surrounded by neuroglial tissue and containing various amounts of adipose tissue bear a striking resemblance to the ependymal structures in RMC. Conclusion: The 13.9% incidence of association between the ependymal structures and filar and caudal types is thought to be because of second ary neurulation failure with the same embryological background as that of RMC. Dorsal and transitional types, resulting from primary neurulation failure, therefore, did not have ependymal structures.

AB - Background: An ependyma-lined canal with surrounding neuroglial tissues can be present in lumbosacral lipomatous malformations; however, the precise embryological significance is still unclear. Method: Six out of 50 patients with lipomatous malformations had ependymal structures. We retrospectively analyzed the clinical, neuroradiological, and histological findings of these patients to demonstrate the relationship with the embryological background of the retained medullary cord (RMC), which normally regresses, but was retained here because of late arrest of secondary neurulation. Results: Five (13.9%) of 36 patients with filar and caudal types and 1 of 3 lipomyelomeningoceles had ependymal structures, while none with dorsal and transitional types had these tissues. Histologically, the ependymal structures surrounded by neuroglial tissue and containing various amounts of adipose tissue bear a striking resemblance to the ependymal structures in RMC. Conclusion: The 13.9% incidence of association between the ependymal structures and filar and caudal types is thought to be because of second ary neurulation failure with the same embryological background as that of RMC. Dorsal and transitional types, resulting from primary neurulation failure, therefore, did not have ependymal structures.

UR - http://www.scopus.com/inward/record.url?scp=85056484641&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85056484641&partnerID=8YFLogxK

U2 - 10.1159/000494029

DO - 10.1159/000494029

M3 - Article

C2 - 30391938

AN - SCOPUS:85056484641

VL - 53

SP - 387

EP - 394

JO - Pediatric Neurosurgery

JF - Pediatric Neurosurgery

SN - 1016-2291

IS - 6

ER -