Epigenetic Regulation of Human Neural Stem Cell Differentiation

研究成果: Chapter in Book/Report/Conference proceedingChapter

4 被引用数 (Scopus)

抄録

Emerging evidence has demonstrated that epigenetic programs influence many aspects of neural stem cell (NSC) behavior, including proliferation and differentiation. It is becoming apparent that epigenetic mechanisms, such as DNA methylation, histone modifications, and noncoding RNA expression, are spatiotemporally regulated and that these intracellular programs, in concert with extracellular signals, ensure appropriate gene activation. Here we summarize recent advances in understanding of the epigenetic regulation of human NSCs directly isolated from the brain or produced from pluripotent stem cells (embryonic and induced pluripotent stem cells, respectively).

本文言語英語
ホスト出版物のタイトルResults and Problems in Cell Differentiation
出版社Springer Verlag
ページ125-136
ページ数12
DOI
出版ステータス出版済み - 2018

出版物シリーズ

名前Results and Problems in Cell Differentiation
66
ISSN(印刷版)0080-1844
ISSN(電子版)1861-0412

All Science Journal Classification (ASJC) codes

  • 発生生物学
  • 細胞生物学

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