Epithelial-myoepithelial carcinoma arising in pleomorphic adenoma of the palate

Cui Ying Li, Kanemitsu Shirasuna, Hiroaki Ishibashi, Hideki Nakayama, Tamotsu Kiyoshima

研究成果: ジャーナルへの寄稿記事

10 引用 (Scopus)

抄録

A case of epithelial-myoepithelial carcinoma (EMC) in pleomorphic adenoma (PA) occurring in the palate of a 72-year-old woman is reported. The tumor was composed of 2 different components, PA and EMC, accounting for approximately 40% and 60% of the whole tumor, respectively. The EMC showed multiple tubular or solid nests, which were separated by a basement membrane and consisted of variable proportions of 2 cell types, cuboidal epithelial cells positive for cytokeratin and clear myoepithelial cells positive for glial fibrillary acid protein, whereas the myoepithelial nests of PA intermingled with hyaline and myxoid stroma. The malignancy was demonstrated by convincing evidence of invasion into the submucosa, although the EMC component was mostly surrounded by the PA components. An increased immunoreactivity of proliferating cell nuclear antigen in the EMC area in comparison to the PA area also suggested EMC arising in a PA.

元の言語英語
記事番号49168
ページ(範囲)460-465
ページ数6
ジャーナルOral surgery, oral medicine, oral pathology, oral radiology, and endodontics
90
発行部数4
DOI
出版物ステータス出版済み - 1 1 2000
外部発表Yes

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Pleomorphic Adenoma
Palate
Carcinoma
Neoplasms
Hyalin
Glial Fibrillary Acidic Protein
Proliferating Cell Nuclear Antigen
Keratins
Basement Membrane
Epithelial Cells

All Science Journal Classification (ASJC) codes

  • Surgery
  • Oral Surgery
  • Otorhinolaryngology
  • Dentistry(all)

これを引用

Epithelial-myoepithelial carcinoma arising in pleomorphic adenoma of the palate. / Li, Cui Ying; Shirasuna, Kanemitsu; Ishibashi, Hiroaki; Nakayama, Hideki; Kiyoshima, Tamotsu.

:: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 巻 90, 番号 4, 49168, 01.01.2000, p. 460-465.

研究成果: ジャーナルへの寄稿記事

Li, Cui Ying ; Shirasuna, Kanemitsu ; Ishibashi, Hiroaki ; Nakayama, Hideki ; Kiyoshima, Tamotsu. / Epithelial-myoepithelial carcinoma arising in pleomorphic adenoma of the palate. :: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. 2000 ; 巻 90, 番号 4. pp. 460-465.
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abstract = "A case of epithelial-myoepithelial carcinoma (EMC) in pleomorphic adenoma (PA) occurring in the palate of a 72-year-old woman is reported. The tumor was composed of 2 different components, PA and EMC, accounting for approximately 40{\%} and 60{\%} of the whole tumor, respectively. The EMC showed multiple tubular or solid nests, which were separated by a basement membrane and consisted of variable proportions of 2 cell types, cuboidal epithelial cells positive for cytokeratin and clear myoepithelial cells positive for glial fibrillary acid protein, whereas the myoepithelial nests of PA intermingled with hyaline and myxoid stroma. The malignancy was demonstrated by convincing evidence of invasion into the submucosa, although the EMC component was mostly surrounded by the PA components. An increased immunoreactivity of proliferating cell nuclear antigen in the EMC area in comparison to the PA area also suggested EMC arising in a PA.",
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N2 - A case of epithelial-myoepithelial carcinoma (EMC) in pleomorphic adenoma (PA) occurring in the palate of a 72-year-old woman is reported. The tumor was composed of 2 different components, PA and EMC, accounting for approximately 40% and 60% of the whole tumor, respectively. The EMC showed multiple tubular or solid nests, which were separated by a basement membrane and consisted of variable proportions of 2 cell types, cuboidal epithelial cells positive for cytokeratin and clear myoepithelial cells positive for glial fibrillary acid protein, whereas the myoepithelial nests of PA intermingled with hyaline and myxoid stroma. The malignancy was demonstrated by convincing evidence of invasion into the submucosa, although the EMC component was mostly surrounded by the PA components. An increased immunoreactivity of proliferating cell nuclear antigen in the EMC area in comparison to the PA area also suggested EMC arising in a PA.

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