Epstein-barr virus load in cerebrospinal fluid of patients with chronic active epstein-barr virus infection

Shouichi Ohga; Masafumi Sanefuji; Masataka Ishimura; Akihiko Nomura; Hiroyuki Torisu; Ryutaro Kira; Hidetoshi Takada; Yumi Mizuno; Yukumasa Kazuyama; Toshiro Hara

doi:10.1097/INF.0b013e318178d21e

Epstein-barr virus load in cerebrospinal fluid of patients with chronic active epstein-barr virus infection

Shouichi Ohga, Masafumi Sanefuji, Masataka Ishimura, Akihiko Nomura, Hiroyuki Torisu, Ryutaro Kira, Hidetoshi Takada, Yumi Mizuno, Yukumasa Kazuyama, Toshiro Hara

研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

5 被引用数 (Scopus)

抄録

Chronic active Epstein-Barr virus (EBV) infection is a rare chronic mononucleosis syndrome involving clonally proliferating EBV-infected T-/NK-cells. EBV DNA was quantified in nonpleocytotic cerebrospinal fluid (CSF) of 9 patients. Three patients with neurologic and/or neuroimaging abnormalities showed high CSF copy numbers. In 1 patient, CSF copy number exceeded the peripheral blood value. CSF EBV-load may predict the central nervous system involvement of EBVT-/NK-cells.

本文言語	英語
ページ（範囲）	1027-1030
ページ数	4
ジャーナル	Pediatric Infectious Disease Journal
巻	27
号	11
DOI	https://doi.org/10.1097/INF.0b013e318178d21e
出版ステータス	出版済み - 11月 2008

!!!All Science Journal Classification (ASJC) codes

小児科学、周産期医学および子どもの健康
微生物学（医療）
感染症

UN SDG

この成果は、次の持続可能な開発目標に貢献しています

文献へのアクセス

10.1097/INF.0b013e318178d21e

他のファイルとリンク

引用スタイル

@article{22bc7a93163444f38ee7cae82ddc12f1,

title = "Epstein-barr virus load in cerebrospinal fluid of patients with chronic active epstein-barr virus infection",

abstract = "Chronic active Epstein-Barr virus (EBV) infection is a rare chronic mononucleosis syndrome involving clonally proliferating EBV-infected T-/NK-cells. EBV DNA was quantified in nonpleocytotic cerebrospinal fluid (CSF) of 9 patients. Three patients with neurologic and/or neuroimaging abnormalities showed high CSF copy numbers. In 1 patient, CSF copy number exceeded the peripheral blood value. CSF EBV-load may predict the central nervous system involvement of EBVT-/NK-cells.",

author = "Shouichi Ohga and Masafumi Sanefuji and Masataka Ishimura and Akihiko Nomura and Hiroyuki Torisu and Ryutaro Kira and Hidetoshi Takada and Yumi Mizuno and Yukumasa Kazuyama and Toshiro Hara",

year = "2008",

month = nov,

doi = "10.1097/INF.0b013e318178d21e",

language = "English",

volume = "27",

pages = "1027--1030",

journal = "Pediatric Infectious Disease Journal",

issn = "0891-3668",

publisher = "Lippincott Williams and Wilkins",

number = "11",

}

TY - JOUR

T1 - Epstein-barr virus load in cerebrospinal fluid of patients with chronic active epstein-barr virus infection

AU - Ohga, Shouichi

AU - Sanefuji, Masafumi

AU - Ishimura, Masataka

AU - Nomura, Akihiko

AU - Torisu, Hiroyuki

AU - Kira, Ryutaro

AU - Takada, Hidetoshi

AU - Mizuno, Yumi

AU - Kazuyama, Yukumasa

AU - Hara, Toshiro

PY - 2008/11

Y1 - 2008/11

N2 - Chronic active Epstein-Barr virus (EBV) infection is a rare chronic mononucleosis syndrome involving clonally proliferating EBV-infected T-/NK-cells. EBV DNA was quantified in nonpleocytotic cerebrospinal fluid (CSF) of 9 patients. Three patients with neurologic and/or neuroimaging abnormalities showed high CSF copy numbers. In 1 patient, CSF copy number exceeded the peripheral blood value. CSF EBV-load may predict the central nervous system involvement of EBVT-/NK-cells.

AB - Chronic active Epstein-Barr virus (EBV) infection is a rare chronic mononucleosis syndrome involving clonally proliferating EBV-infected T-/NK-cells. EBV DNA was quantified in nonpleocytotic cerebrospinal fluid (CSF) of 9 patients. Three patients with neurologic and/or neuroimaging abnormalities showed high CSF copy numbers. In 1 patient, CSF copy number exceeded the peripheral blood value. CSF EBV-load may predict the central nervous system involvement of EBVT-/NK-cells.

UR - http://www.scopus.com/inward/record.url?scp=58149166800&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=58149166800&partnerID=8YFLogxK

U2 - 10.1097/INF.0b013e318178d21e

DO - 10.1097/INF.0b013e318178d21e

M3 - Article

C2 - 18833029

AN - SCOPUS:58149166800

VL - 27

SP - 1027

EP - 1030

JO - Pediatric Infectious Disease Journal

JF - Pediatric Infectious Disease Journal

SN - 0891-3668

IS - 11

ER -

Epstein-barr virus load in cerebrospinal fluid of patients with chronic active epstein-barr virus infection

抄録

!!!All Science Journal Classification (ASJC) codes

UN SDG

文献へのアクセス

他のファイルとリンク

フィンガープリント

引用スタイル