Establishment of a Feline T-Lymphoblastoid Cell Line Susceptible to Feline Immunodeficiency Viruses

Satoshi Fujimoto, Mahito Masuda, Etsuro Ono, Hiroshi Kida, Yukio Shimizu

研究成果: Contribution to journalArticle査読

1 被引用数 (Scopus)

抄録

A feline T-lymphoblastoid cell line susceptible to feline immunodeficiency viruses (FIV) was established and designated as Yu-1 cells. Yu-1 cells continued to grow over one year with more than 100 successive passages in the presence of human recombinant interleukin-2. Surface antigens of Yu-1 cells were feline Pan-T+, CD4+, and CD8-. Susceptibility of Yu-1 cells to FIV strains were higher than that of the primary culture of the feline peripheral blood mononuclear cells, indicating that this cell line should be useful for isolation, propagation, and neutralization test of FIV.

本文言語英語
ページ(範囲)415-418
ページ数4
ジャーナルMICROBIOLOGY and IMMUNOLOGY
37
5
DOI
出版ステータス出版済み - 1993
外部発表はい

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology
  • Virology

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