Establishment of portable immunoassay system for early diagnosis

Toshihiro Kasama, Yutaka Hasegawa, Hiroyuki Matsumoto, Haruyasu Kondo, Tsutomu Ozawa, Noritada Kaji, Manabu Tokeshi, Yoshinobu Baba

研究成果: 書籍/レポート タイプへの寄稿会議への寄与

抄録

We have developed immunopillar devices for rapid and easy-to-use immunoassay with pM-fM detection sensitivity, but long total assay time (sample-in-answer-out) and the compatibility with a portable detection system have still remained as major problems toward the point-of-care testing (POCT). We report here next generation immunopillar devices and portable detection system suitable for them. Thin structure of those devices allowed us to wash nonspecifically bound antigens and fluorescent-labeled secondary antibodies in a minute, resulting in the dramatic reduction in the total assay time. In addition, by using the portable detection system, we gained the concentrations of C-reactive protein in human sera while preserving pM detection sensitivity. The total assay time was 20 minutes per sample. Our immunoassay system possesses the potential for use in POCT.

本文言語英語
ホスト出版物のタイトル2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013
出版社IEEE Computer Society
ISBN(印刷版)9781479915293
DOI
出版ステータス出版済み - 2013
外部発表はい
イベント2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013 - Nagoya, 日本
継続期間: 11月 10 201311月 13 2013

出版物シリーズ

名前2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013

その他

その他2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013
国/地域日本
CityNagoya
Period11/10/1311/13/13

!!!All Science Journal Classification (ASJC) codes

  • 電子工学および電気工学

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