Establishment of portable immunoassay system for early diagnosis

Toshihiro Kasama, Yutaka Hasegawa, Hiroyuki Matsumoto, Haruyasu Kondo, Tsutomu Ozawa, Noritada Kaji, Manabu Tokeshi, Yoshinobu Baba

研究成果: 著書/レポートタイプへの貢献会議での発言

抄録

We have developed immunopillar devices for rapid and easy-to-use immunoassay with pM-fM detection sensitivity, but long total assay time (sample-in-answer-out) and the compatibility with a portable detection system have still remained as major problems toward the point-of-care testing (POCT). We report here next generation immunopillar devices and portable detection system suitable for them. Thin structure of those devices allowed us to wash nonspecifically bound antigens and fluorescent-labeled secondary antibodies in a minute, resulting in the dramatic reduction in the total assay time. In addition, by using the portable detection system, we gained the concentrations of C-reactive protein in human sera while preserving pM detection sensitivity. The total assay time was 20 minutes per sample. Our immunoassay system possesses the potential for use in POCT.

元の言語英語
ホスト出版物のタイトル2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013
出版者IEEE Computer Society
ISBN(印刷物)9781479915293
DOI
出版物ステータス出版済み - 1 1 2013
外部発表Yes
イベント2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013 - Nagoya, 日本
継続期間: 11 10 201311 13 2013

出版物シリーズ

名前2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013

その他

その他2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013
日本
Nagoya
期間11/10/1311/13/13

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Assays
Testing
Antigens
Antibodies
Proteins

All Science Journal Classification (ASJC) codes

  • Electrical and Electronic Engineering

これを引用

Kasama, T., Hasegawa, Y., Matsumoto, H., Kondo, H., Ozawa, T., Kaji, N., ... Baba, Y. (2013). Establishment of portable immunoassay system for early diagnosis. : 2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013 [6710451] (2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013). IEEE Computer Society. https://doi.org/10.1109/MHS.2013.6710451

Establishment of portable immunoassay system for early diagnosis. / Kasama, Toshihiro; Hasegawa, Yutaka; Matsumoto, Hiroyuki; Kondo, Haruyasu; Ozawa, Tsutomu; Kaji, Noritada; Tokeshi, Manabu; Baba, Yoshinobu.

2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013. IEEE Computer Society, 2013. 6710451 (2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013).

研究成果: 著書/レポートタイプへの貢献会議での発言

Kasama, T, Hasegawa, Y, Matsumoto, H, Kondo, H, Ozawa, T, Kaji, N, Tokeshi, M & Baba, Y 2013, Establishment of portable immunoassay system for early diagnosis. : 2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013., 6710451, 2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013, IEEE Computer Society, 2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013, Nagoya, 日本, 11/10/13. https://doi.org/10.1109/MHS.2013.6710451
Kasama T, Hasegawa Y, Matsumoto H, Kondo H, Ozawa T, Kaji N その他. Establishment of portable immunoassay system for early diagnosis. : 2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013. IEEE Computer Society. 2013. 6710451. (2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013). https://doi.org/10.1109/MHS.2013.6710451
Kasama, Toshihiro ; Hasegawa, Yutaka ; Matsumoto, Hiroyuki ; Kondo, Haruyasu ; Ozawa, Tsutomu ; Kaji, Noritada ; Tokeshi, Manabu ; Baba, Yoshinobu. / Establishment of portable immunoassay system for early diagnosis. 2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013. IEEE Computer Society, 2013. (2013 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2013).
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