Establishment of Treatment of Retinal Vein Occlusion by Physical Stimuli of Electrically-Induced Bubbles

Mei Sumimoto, Daisuke Matsumura, Keita Ichikawa, Keiko Miwa, Hideyasu Oh, Yasuhiro Moriizumi, Yoko Yamanishi

研究成果: Chapter in Book/Report/Conference proceedingConference contribution

抄録

For this study, a novel treatment of retinal vein occlusion by physical stimuli of electrically-induced bubbles was proposed. Our device can apply local and minimally-invasive physical stimuli to retinal minute blood vessels with a diameter of about 100 μm, utilizing the impact pressure when microbubbles collapse. Furthermore, it is possible to sense the approach of the device to the target by measuring the capacitance. Vascular vessels of chick embryos whose size is similar to that of the retinal vein, and retinal veins of pig were used as in-vitro and in-vivo model respectively. Also, micro-vascular occlusion models were successfully operated and local physical stimuli was applied to the blood clot which is artificially produced. The 60% of reperfusion against the initial amount was confirmed by blood flow measurement for both in vitro and in vivo environment.

本文言語英語
ホスト出版物のタイトル2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII
出版社Institute of Electrical and Electronics Engineers Inc.
ページ809-812
ページ数4
ISBN(電子版)9781728120072
DOI
出版ステータス出版済み - 6 2019
イベント20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII - Berlin, ドイツ
継続期間: 6 23 20196 27 2019

出版物シリーズ

名前2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII

会議

会議20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII
国/地域ドイツ
CityBerlin
Period6/23/196/27/19

All Science Journal Classification (ASJC) codes

  • プロセス化学およびプロセス工学
  • 分光学
  • 電子工学および電気工学
  • 機械工学
  • 電子材料、光学材料、および磁性材料
  • 制御と最適化
  • 器械工学

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