Establishment of vertebrate left-right asymmetry

Hiroshi Hamada, Chikara Meno, Daisuke Watanabe, Yukio Saijoh

研究成果: Contribution to journalReview article査読

414 被引用数 (Scopus)

抄録

The generation of morphological, such as left-right, asymmetry during development is an integral part of the establishment of a body plan. Until recently, the molecular basis of left-right asymmetry was a mystery, but studies indicate that Nodal and the Lefty proteins, transforming growth factor-β-related molecules, have a central role in generating asymmetric signals. Although the initial mechanism of symmetry breaking remains unknown, developmental biologists are beginning to analyse the pathway that leads to left-right asymmetry establishment and maintenance.

本文言語英語
ページ(範囲)103-113
ページ数11
ジャーナルNature Reviews Genetics
3
2
DOI
出版ステータス出版済み - 5 23 2002
外部発表はい

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Genetics
  • Genetics(clinical)

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