Evaluating protein sequence signatures inferred from protein-protein interaction data by gene ontology annotations

Osamu Maruyama, Hideki Hirakawa, Takao Iwayanagi, Yoshiko Ishida, Shizu Takeda, Jun Otomo, Satoru Kuhara

研究成果: Chapter in Book/Report/Conference proceedingConference contribution

抄録

We propose a systematic method to find sequence signatures of proteins which share a common interacting partner, using a protein similarity measure based on gene ontology (GO) annotations. In a computational experiment on our original human data set of protein-protein interactions determined by Y2H assays, we have succeeded in discovering convincing candidates for interacting sites and other functional regions.

本文言語英語
ホスト出版物のタイトルProceedings - IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2008
ページ417-420
ページ数4
DOI
出版ステータス出版済み - 12 1 2008
イベント2008 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2008 - Philadelphia, PA, 米国
継続期間: 11 3 200811 5 2008

その他

その他2008 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2008
Country米国
CityPhiladelphia, PA
Period11/3/0811/5/08

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Information Systems
  • Biomedical Engineering

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