Evaluation of pluripotency in human intenstinal cells by microfluidic-based single cell deformability analysis

Miyu Terada, Sachiko Ide, Toyohiro Naito, Michiya Matsusaki, Noritada Kaji

研究成果: Chapter in Book/Report/Conference proceedingConference contribution

抄録

In this study, we have developed a microfluidic device that can analyze the pluripotency of cells by measuring the cell deformability based on ionic current sensing at a single cell level. We successfully identified human colon cancer cells (HT29) with high and low pluripotency based on the deformability information and the result was confirmed by a biochemical assay, Aldehyde Dehydrogenase (ALDH) assay, which is an important biomarker of the pluripotency.

本文言語英語
ホスト出版物のタイトルMicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences
出版社Chemical and Biological Microsystems Society
ページ1049-1050
ページ数2
ISBN(電子版)9781733419017
出版ステータス出版済み - 2020
イベント24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020 - Virtual, Online
継続期間: 10 4 202010 9 2020

出版物シリーズ

名前MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences

会議

会議24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020
CityVirtual, Online
Period10/4/2010/9/20

All Science Journal Classification (ASJC) codes

  • Chemical Engineering (miscellaneous)
  • Bioengineering
  • Chemistry(all)
  • Control and Systems Engineering

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