Evolutionary design of oscillatory genetic networks in silico

Yuki Naruse, Hiroyuki Hamada, Taizo Hanai, Hitoshi Iba

研究成果: Chapter in Book/Report/Conference proceedingConference contribution

1 被引用数 (Scopus)

抄録

The design of genetic networks has been studied for implementing desired biological systems, and in particular, some researchers have proposed automatic design methods using optimization techniques. However, it is difficult to implement genetic networks designed by previous methods due to overly simplified model descriptions whose parameters are infeasible in the real world. Additionally, the methods do not ensure robustness against parameter perturbation. In this paper, we propose a two-stage design method and a fitness function evaluating robustness to create genetic networks which can be implemented experimentally. Further, we suggest the knowledge about robust network structures from results of optimization.

本文言語英語
ホスト出版物のタイトル2015 IEEE Congress on Evolutionary Computation, CEC 2015 - Proceedings
出版社Institute of Electrical and Electronics Engineers Inc.
ページ1596-1603
ページ数8
ISBN(電子版)9781479974924
DOI
出版ステータス出版済み - 9 10 2015
イベントIEEE Congress on Evolutionary Computation, CEC 2015 - Sendai, 日本
継続期間: 5 25 20155 28 2015

その他

その他IEEE Congress on Evolutionary Computation, CEC 2015
Country日本
CitySendai
Period5/25/155/28/15

All Science Journal Classification (ASJC) codes

  • Computer Science Applications
  • Computational Mathematics

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