Evolutionary design of oscillatory genetic networks in silico

Yuki Naruse, Hiroyuki Hamada, Taizo Hanai, Hitoshi Iba

研究成果: 著書/レポートタイプへの貢献会議での発言

1 引用 (Scopus)

抄録

The design of genetic networks has been studied for implementing desired biological systems, and in particular, some researchers have proposed automatic design methods using optimization techniques. However, it is difficult to implement genetic networks designed by previous methods due to overly simplified model descriptions whose parameters are infeasible in the real world. Additionally, the methods do not ensure robustness against parameter perturbation. In this paper, we propose a two-stage design method and a fitness function evaluating robustness to create genetic networks which can be implemented experimentally. Further, we suggest the knowledge about robust network structures from results of optimization.

元の言語英語
ホスト出版物のタイトル2015 IEEE Congress on Evolutionary Computation, CEC 2015 - Proceedings
出版者Institute of Electrical and Electronics Engineers Inc.
ページ1596-1603
ページ数8
ISBN(電子版)9781479974924
DOI
出版物ステータス出版済み - 9 10 2015
イベントIEEE Congress on Evolutionary Computation, CEC 2015 - Sendai, 日本
継続期間: 5 25 20155 28 2015

その他

その他IEEE Congress on Evolutionary Computation, CEC 2015
日本
Sendai
期間5/25/155/28/15

Fingerprint

Genetic Network
Design Method
Robustness
Two-stage Design
Parameter Perturbation
Biological systems
Fitness Function
Biological Systems
Network Structure
Optimization Techniques
Optimization
Design
Model

All Science Journal Classification (ASJC) codes

  • Computer Science Applications
  • Computational Mathematics

これを引用

Naruse, Y., Hamada, H., Hanai, T., & Iba, H. (2015). Evolutionary design of oscillatory genetic networks in silico. : 2015 IEEE Congress on Evolutionary Computation, CEC 2015 - Proceedings (pp. 1596-1603). [7257078] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/CEC.2015.7257078

Evolutionary design of oscillatory genetic networks in silico. / Naruse, Yuki; Hamada, Hiroyuki; Hanai, Taizo; Iba, Hitoshi.

2015 IEEE Congress on Evolutionary Computation, CEC 2015 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2015. p. 1596-1603 7257078.

研究成果: 著書/レポートタイプへの貢献会議での発言

Naruse, Y, Hamada, H, Hanai, T & Iba, H 2015, Evolutionary design of oscillatory genetic networks in silico. : 2015 IEEE Congress on Evolutionary Computation, CEC 2015 - Proceedings., 7257078, Institute of Electrical and Electronics Engineers Inc., pp. 1596-1603, IEEE Congress on Evolutionary Computation, CEC 2015, Sendai, 日本, 5/25/15. https://doi.org/10.1109/CEC.2015.7257078
Naruse Y, Hamada H, Hanai T, Iba H. Evolutionary design of oscillatory genetic networks in silico. : 2015 IEEE Congress on Evolutionary Computation, CEC 2015 - Proceedings. Institute of Electrical and Electronics Engineers Inc. 2015. p. 1596-1603. 7257078 https://doi.org/10.1109/CEC.2015.7257078
Naruse, Yuki ; Hamada, Hiroyuki ; Hanai, Taizo ; Iba, Hitoshi. / Evolutionary design of oscillatory genetic networks in silico. 2015 IEEE Congress on Evolutionary Computation, CEC 2015 - Proceedings. Institute of Electrical and Electronics Engineers Inc., 2015. pp. 1596-1603
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