Evolutionary relationships and sequence variation of α-amylase variants encoded by duplicated genes in the Amy locus of Drosophila melanogaster

N. Inomata, Hiroki Shibata, E. Okuyama, T. Yamazaki

研究成果: ジャーナルへの寄稿記事

42 引用 (Scopus)

抜粋

To infer the genealogical relationships of α-amylase electromorphs of Drosophila melanogaster, we determined the nucleotide sequences of a collection of electromorphs sampled throughout the world. On average there were 1.0 amino acid substitutions between identical electromorphs and 3.9 between different electromorphs, respectively. We found that the evolution of AMY1 through AMY6 electromorphs occurred by sequential accumulation of single amino acid substitutions each causing one charge difference. The nucleotide diversities at synonymous sites within Amy1, Amy2, Amy3, Amy4 and Amy6 were 0.0321, 0.0000, 0.0355, 0.0059 and 0.0030, respectively. We also obtained evidence of genetic exchanges, such as intrachromosomal recombination, interchromosomal recombination or gene conversion, between the two duplicated Amy genes as well as among the alleles.

元の言語英語
ページ(範囲)237-244
ページ数8
ジャーナルGenetics
141
発行部数1
出版物ステータス出版済み - 1 1 1995

    フィンガープリント

All Science Journal Classification (ASJC) codes

  • Genetics

これを引用