Expanding the synthesizable multisubstituted benzo[b] thiophenes via 6,7-thienobenzynes generated from o -silylaryl triflate-type precursors

Suguru Yoshida, Tomoko Kuribara, Takamoto Morita, Tsubasa Matsuzawa, Kazushi Morimoto, Takuya Kobayashi, Takamitsu Hosoya

研究成果: Contribution to journalArticle査読

13 被引用数 (Scopus)

抄録

Various 2,3-disubstituted 6,7-thienobenzynes have been efficiently generated from the corresponding o-silylaryl triflate-type precursors by activation with fluoride ions. The method has expanded the scope of synthesizable multisubstituted benzothiophenes, including those with various heteroatom substituents, and can be applied to the synthesis of EP4 antagonist analogs.

本文言語英語
ページ(範囲)21754-21758
ページ数5
ジャーナルRSC Advances
8
39
DOI
出版ステータス出版済み - 2018
外部発表はい

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)

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