Exposure to an atomic bomb explosion is a risk factor for in-hospital death after esophagectomy to treat esophageal cancer

Y. Nakashima, K. Takeishi, A. Guntani, E. Tsujita, K. Yoshinaga, A. Matsuyama, M. Hamatake, T. Maeda, S. Tsutsui, H. Matsuda, T. Ishida

研究成果: ジャーナルへの寄稿記事

抄録

Esophagectomy, one of the most invasive of all gastrointestinal operations, is associated with a high frequency of postoperative complications and in-hospital mortality. The purpose of the present study was to determine whether exposure to the atomic bomb explosion at Hiroshima in 1945 might be a preoperative risk factor for in-hospital mortality after esophagectomy in esophageal cancer patients. We thus reviewed the outcomes of esophagectomy in 31 atomic bomb survivors with esophageal cancer and 96 controls (also with cancer but without atomic bomb exposure). We compared the incidences of postoperative complications and in-hospital mortality. Of the clinicopathological features studied, mean patient age was significantly higher in atomic bomb survivors than in controls. Of the postoperative complications noted, atomic bomb survivors experienced a longer mean period of endotracheal intubation and higher incidences of severe pulmonary complications, severe anastomotic leakage, and surgical site infection. The factors associated with in-hospital mortality were exposure to the atomic bomb explosion, pulmonary comorbidities, and electrocardiographic abnormalities. Multivariate analysis revealed that exposure to the atomic bomb explosion was an independent significant preoperative risk factor for in-hospital mortality. Exposure to the atomic bomb explosion is thus a preoperative risk factor for in-hospital death after esophagectomy to treat esophageal cancer.

元の言語英語
ページ(範囲)78-83
ページ数6
ジャーナルDiseases of the Esophagus
28
発行部数1
DOI
出版物ステータス出版済み - 1 1 2015

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Nuclear Weapons
Esophagectomy
Explosions
Esophageal Neoplasms
Hospital Mortality
Survivors
Surgical Wound Infection
Lung
Anastomotic Leak
Intratracheal Intubation
Incidence
Comorbidity
Multivariate Analysis

All Science Journal Classification (ASJC) codes

  • Gastroenterology

これを引用

Exposure to an atomic bomb explosion is a risk factor for in-hospital death after esophagectomy to treat esophageal cancer. / Nakashima, Y.; Takeishi, K.; Guntani, A.; Tsujita, E.; Yoshinaga, K.; Matsuyama, A.; Hamatake, M.; Maeda, T.; Tsutsui, S.; Matsuda, H.; Ishida, T.

:: Diseases of the Esophagus, 巻 28, 番号 1, 01.01.2015, p. 78-83.

研究成果: ジャーナルへの寄稿記事

Nakashima, Y, Takeishi, K, Guntani, A, Tsujita, E, Yoshinaga, K, Matsuyama, A, Hamatake, M, Maeda, T, Tsutsui, S, Matsuda, H & Ishida, T 2015, 'Exposure to an atomic bomb explosion is a risk factor for in-hospital death after esophagectomy to treat esophageal cancer', Diseases of the Esophagus, 巻. 28, 番号 1, pp. 78-83. https://doi.org/10.1111/dote.12159
Nakashima, Y. ; Takeishi, K. ; Guntani, A. ; Tsujita, E. ; Yoshinaga, K. ; Matsuyama, A. ; Hamatake, M. ; Maeda, T. ; Tsutsui, S. ; Matsuda, H. ; Ishida, T. / Exposure to an atomic bomb explosion is a risk factor for in-hospital death after esophagectomy to treat esophageal cancer. :: Diseases of the Esophagus. 2015 ; 巻 28, 番号 1. pp. 78-83.
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