Expression levels of taste-related genes in palate and tongue tip, and involvement of transient receptor potential subfamily M member 5 (TRPM5) in taste sense in chickens

Yuta Yoshida, Fuminori Kawabata, Yuko Kawabata, Shotaro Nishimura, Shoji Tabata

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

抄録

The elucidation of the mechanisms underlying the taste sense of chickens will contribute to improvements in poultry feeding, because the molecular mechanism of chickens’ taste sense defines the feeding behavior of chickens. Here we focused on the gene expressions in two different oral tissues of chickens – the palate, which contains many taste buds, and the tongue tip, which contains few taste buds. Using the quantitative real-time polymerase chain reaction method, we found that the molecular markers for taste buds of chickens, that is α-gustducin and vimentin, were expressed significantly highly in the palate compared to the tongue tip. Our analyses also revealed that transient receptor potential subfamily M member 5 (TRPM5), a cation channel involved in taste transduction in mammals, was also highly expressed in the palate compared to the tongue tip. Our findings demonstrated that the expression patterns of these genes were significantly correlated. We showed that the aversion to bitter solution was alleviated by a TRPM5 inhibitor in behavior of chickens. Taken together, our findings enabled us to develop a simple method for screening taste-related genes in chickens. The use of this method demonstrated that TRPM5 was involved in chickens’ taste transduction, and that a TRPM5 inhibitor can alleviate chickens’ bitter taste perception of feed ingredients.

元の言語英語
ページ(範囲)441-447
ページ数7
ジャーナルAnimal Science Journal
89
発行部数2
DOI
出版物ステータス出版済み - 2 1 2018

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palate
Palate
tongue
Tongue
Chickens
chickens
receptors
Taste Buds
Genes
genes
palps
poultry feeding
Taste Perception
Gene Expression
vimentin
Feeding Behavior
Vimentin
Poultry
feeding behavior
Cations

All Science Journal Classification (ASJC) codes

  • Agricultural and Biological Sciences(all)

これを引用

Expression levels of taste-related genes in palate and tongue tip, and involvement of transient receptor potential subfamily M member 5 (TRPM5) in taste sense in chickens. / Yoshida, Yuta; Kawabata, Fuminori; Kawabata, Yuko; Nishimura, Shotaro; Tabata, Shoji.

:: Animal Science Journal, 巻 89, 番号 2, 01.02.2018, p. 441-447.

研究成果: ジャーナルへの寄稿記事

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