Expression of mRNA for activin-binding protein (follistatin) during early embryonic development of Xenopus laevis

Kosuke Tashiro, Ryutaro Yamada, Misaki Asano, Makoto Hashimoto, Masami Muramatsu, Koichiro Shiokawa

研究成果: ジャーナルへの寄稿記事

42 引用 (Scopus)

抄録

Follistatin is a specific activin-binding protein and is supposed to control activin functions. During Xenopus embryonic development, activin is thought to act as a natural mesoderm-inducing factor. We isolated here the Xenopus follistatin cDNA from Xenopus ovary cDNA library and studied the expression of Xenopus follistatin gene during the course of early embryonic development. The Xenopus follistatin has an 84 % homology at the level of deduced amino acid sequence with human and porcine follistatin. Its 3.5 kb mRNA is first expressed at the gastrula stage, when the expression of activin mRNA becomes first detectable, and increased thereafter. Another species of 2 kb mRNA become detectable from early neurula and also increased dramatically in tadpole. These results suggest that the follistatin acts also as a regulator of activin in inductive interactions during amphibian embryonic development.

元の言語英語
ページ(範囲)1022-1027
ページ数6
ジャーナルBiochemical and Biophysical Research Communications
174
発行部数2
DOI
出版物ステータス出版済み - 1 31 1991

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Follistatin
Xenopus laevis
Embryonic Development
Xenopus
Activins
Messenger RNA
Gastrula
Amphibians
Mesoderm
Gene Library
Larva
Amino Acid Sequence
Ovary
Swine
Complementary DNA
Genes
Amino Acids

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

これを引用

Expression of mRNA for activin-binding protein (follistatin) during early embryonic development of Xenopus laevis. / Tashiro, Kosuke; Yamada, Ryutaro; Asano, Misaki; Hashimoto, Makoto; Muramatsu, Masami; Shiokawa, Koichiro.

:: Biochemical and Biophysical Research Communications, 巻 174, 番号 2, 31.01.1991, p. 1022-1027.

研究成果: ジャーナルへの寄稿記事

Tashiro, Kosuke ; Yamada, Ryutaro ; Asano, Misaki ; Hashimoto, Makoto ; Muramatsu, Masami ; Shiokawa, Koichiro. / Expression of mRNA for activin-binding protein (follistatin) during early embryonic development of Xenopus laevis. :: Biochemical and Biophysical Research Communications. 1991 ; 巻 174, 番号 2. pp. 1022-1027.
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