Extension and measurements on a phospholipid vesicle by use of dual-beam optical tweezers

Masatoshi Ichikawa, Yoko Shitamichi, Yasuyuki Kimura

研究成果: Chapter in Book/Report/Conference proceedingConference contribution

1 被引用数 (Scopus)

抄録

A vesicle whose membrane is composed of a Phospholipid bilayer is called as a liposome. Since the fundamental structure of the membrane is the same as cell membranes, liposomes have been intensively studied as a simple model of live-cells. Here, we study the mechanical property of a micrometer-sized giant liposome through extending a single liposome from the inside by use of dual-beam optical tweezers. As the liposome is extended, the shape gradually changes from a sphere to a lemon-shape, and finally, a tubular membrane projection is exhibited. The surface tension and the bending rigidity of the lipid membrane are obtained from the measured force-extension curve. The present paper reviews both experimental and theoretical bases of this extension measurement method on the liposome with our experimental data.

本文言語英語
ホスト出版物のタイトル2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008, with Symposium on "COE for Education and Research of Micro-Nano Mechatronics"
ページ71-76
ページ数6
DOI
出版ステータス出版済み - 12 1 2008
イベント2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008, with Symposium on "COE for Education and Research of Micro-Nano Mechatronics", Symposium on "System Cell Engineering by Multi-scale Manipulation" - Nagoya, 日本
継続期間: 11 6 200811 9 2008

出版物シリーズ

名前2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008

その他

その他2008 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2008, with Symposium on "COE for Education and Research of Micro-Nano Mechatronics", Symposium on "System Cell Engineering by Multi-scale Manipulation"
Country日本
CityNagoya
Period11/6/0811/9/08

All Science Journal Classification (ASJC) codes

  • Computer Vision and Pattern Recognition
  • Human-Computer Interaction
  • Electrical and Electronic Engineering

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