Extension of the lifespan of caenorhabditis elegans by the use of electrolyzed reduced water

Hanxu Yan, Huaize Tian, Tomoya Kinjo, Takeki Hamasaki, Kosuke Tomimatsu, Noboru Nakamichi, Kiichiro Teruya, Shigeru Kabayama, Sanetaka Shirahata

研究成果: ジャーナルへの寄稿 › 記事

14 引用 (Scopus)

抄録

Electrolyzed reduced water (ERW) has attracted much attention because of its therapeutic effects. In the present study, a new culture medium, which we designated Water medium, was developed to elucidate the effects of ERW on the lifespan of Caenorhabditis elegans. Wild-type C. elegans had a significantly shorter lifespan in Water medium than in conventional S medium. However, worms cultured in ERW-Water medium exhibited a significantly extended lifespan (from 11% to 41%) compared with worms cultured in ultrapure water-Water medium. There was no difference between the lifespans of worms cultured in ERW-S medium and ultrapure water-S medium. Nematodes cultured in ultrapure water-Water medium showed significantly higher levels of reactive oxygen species than those cultured in ultrapure water-S medium. Moreover, ERW-Water medium significantly reduced the ROS accumulation induced in the worms by paraquat, suggesting that ERW-Water medium extends the longevity of nematodes at least partly by scavenging ROS.

元の言語英語
ページ（範囲）2011-2015
ページ数5
ジャーナルBioscience, Biotechnology and Biochemistry
巻74
発行部数10
DOI
出版物ステータス出版済み - 11 8 2010

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Caenorhabditis elegans
Water
Paraquat
Scavenging
Therapeutic Uses

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

これを引用

Yan, H., Tian, H., Kinjo, T., Hamasaki, T., Tomimatsu, K., Nakamichi, N., ... Shirahata, S. (2010). Extension of the lifespan of caenorhabditis elegans by the use of electrolyzed reduced water. Bioscience, Biotechnology and Biochemistry, 74(10), 2011-2015. https://doi.org/10.1271/bbb.100250

Extension of the lifespan of caenorhabditis elegans by the use of electrolyzed reduced water. / Yan, Hanxu; Tian, Huaize; Kinjo, Tomoya; Hamasaki, Takeki; Tomimatsu, Kosuke; Nakamichi, Noboru; Teruya, Kiichiro; Kabayama, Shigeru; Shirahata, Sanetaka.

：: Bioscience, Biotechnology and Biochemistry, 巻 74, 番号 10, 08.11.2010, p. 2011-2015.

研究成果: ジャーナルへの寄稿 › 記事

Yan, H, Tian, H, Kinjo, T, Hamasaki, T, Tomimatsu, K, Nakamichi, N, Teruya, K, Kabayama, S & Shirahata, S 2010, 'Extension of the lifespan of caenorhabditis elegans by the use of electrolyzed reduced water', Bioscience, Biotechnology and Biochemistry, 巻. 74, 番号 10, pp. 2011-2015. https://doi.org/10.1271/bbb.100250
Yan H, Tian H, Kinjo T, Hamasaki T, Tomimatsu K, Nakamichi N その他. Extension of the lifespan of caenorhabditis elegans by the use of electrolyzed reduced water. Bioscience, Biotechnology and Biochemistry. 2010 11 8;74(10):2011-2015. https://doi.org/10.1271/bbb.100250
Yan, Hanxu ; Tian, Huaize ; Kinjo, Tomoya ; Hamasaki, Takeki ; Tomimatsu, Kosuke ; Nakamichi, Noboru ; Teruya, Kiichiro ; Kabayama, Shigeru ; Shirahata, Sanetaka. / Extension of the lifespan of caenorhabditis elegans by the use of electrolyzed reduced water. ：: Bioscience, Biotechnology and Biochemistry. 2010 ; 巻 74, 番号 10. pp. 2011-2015.
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