TY - JOUR
T1 - Extraction of lactic acid from fermented broth with microporous hollow fiber membranes
AU - Tong, Yanping
AU - Hirata, Makoto
AU - Takanashi, Hirokazu
AU - Hano, Tadashi
AU - Kubota, Fukiko
AU - Goto, Masahiro
AU - Nakashio, Fumiyuki
AU - Matsumoto, Michiaki
PY - 1998/5/27
Y1 - 1998/5/27
N2 - Non-dispersive solvent extraction of lactic acid based on anion-exchange reaction with tri-n-octylmethylammonium chloride dissolved in oleyl alcohol, the optimum extraction reagents selected for extractive fermentation of lactic acid with Lactobacillus rhamnosus, was attempted in a microporous hollow fiber membrane device. A satisfactory recovery of lactic acid from both aqueous solution and actual fermented broth was accomplished, signifying the great potential of integrating the membrane extraction with fermentation process. A theoretical model which took into account the mass transfer resistances across organic and aqueous films and membrane was developed to analyze and predict the extraction behavior. The model prediction was found to be in good agreement with the experimentally observed results.
AB - Non-dispersive solvent extraction of lactic acid based on anion-exchange reaction with tri-n-octylmethylammonium chloride dissolved in oleyl alcohol, the optimum extraction reagents selected for extractive fermentation of lactic acid with Lactobacillus rhamnosus, was attempted in a microporous hollow fiber membrane device. A satisfactory recovery of lactic acid from both aqueous solution and actual fermented broth was accomplished, signifying the great potential of integrating the membrane extraction with fermentation process. A theoretical model which took into account the mass transfer resistances across organic and aqueous films and membrane was developed to analyze and predict the extraction behavior. The model prediction was found to be in good agreement with the experimentally observed results.
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U2 - 10.1016/S0376-7388(98)00016-7
DO - 10.1016/S0376-7388(98)00016-7
M3 - Article
AN - SCOPUS:0032572020
VL - 143
SP - 81
EP - 91
JO - Journal of Membrane Science
JF - Journal of Membrane Science
SN - 0376-7388
IS - 1-2
ER -