Fabrication of capillary-like network in a matrix of water-soluble polymer using poly(methyl methacrylate) microfibers

Takayuki Takei, Naoya Kishihara, Hiroyuki Ijima, Koei Kawakami

研究成果: Contribution to journalArticle

7 引用 (Scopus)

抜粋

Poly(methyl methacrylate) (PMMA) microfibers were used as a template for development of a capillary-like network in agarose hydrogel. Microfibers with diameter 10-20 μm, which is comparable to the diameter of native capillary vessels, were fabricated using a wet spinning technique. The microfibers were embedded in agarose gel and dissolved by immersing the gel in dichloromethane. The resultant microchannels in the gel had the same diameter as the microfibers, and allowed an aqueous solution to be perfused through the gel. The methodology is promising for fabricating a capillary-like network in tissue engineering scaffolds of various water-soluble polymers.

元の言語英語
ページ(範囲)66-69
ページ数4
ジャーナルArtificial Cells, Blood Substitutes, and Biotechnology
40
発行部数1-2
DOI
出版物ステータス出版済み - 2 1 2012

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biomedical Engineering

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