Fabrication of fork-shaped retinal stimulator integrated with CMOS microchips for extension of viewing angle

Toshihiko Noda, Kiyotaka Sasagawa, Takashi Tokuda, Hiroyuki Kanda, Yasuo Terasawa, Hiroyuki Tashiro, Takashi Fujikado, Jun Ohta

研究成果: Contribution to journalArticle査読

10 被引用数 (Scopus)

抄録

A fork-shaped retinal stimulator for a wide viewing angle was fabricated and demonstrated. This stimulator has two flexible fork elements, each with a stimulus head. The two fork elements can be implanted at different places in the eyeball to cover a wider area of the retina. The stimulus head has stimulus electrodes with the same shape as the electrodes utilized in a clinical trial for six weeks. Complementary metal-oxide semiconductor (CMOS) microchips were integrated into the stimulator and mounted next to the stimulus electrodes. Since stimulus current generators are integrated into the microchips, no external wires for stimulus current are required. A multiplexer, which reduces the number of wirings, was also integrated into the microchips. The fabricated stimulator was evaluated through in vivo animal experiments. The stimulator was successfully implanted in two places of the eyeball. Retinal stimulation by the device evoked nerve responses from optic chiasma and produced a specific peak of evoked potential. Experimental results demonstrate the proof of concept of a fork-shaped stimulator and suggest that the same device configuration can realize multiple forkshaped stimulators for a wider viewing angle. Moreover, increasing the number of fork elements of the multifork stimulator without additional wirings becomes possible.

本文言語英語
ページ(範囲)637-648
ページ数12
ジャーナルSensors and Materials
26
8
出版ステータス出版済み - 1 1 2014

All Science Journal Classification (ASJC) codes

  • 器械工学
  • 材料科学(全般)

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