Fabrication of interconnected pore forming α-tricalcium phosphate foam granules cement

Khairul Anuar Shariff, Kanji Tsuru, Kunio Ishikawa

研究成果: Contribution to journalArticle査読

10 被引用数 (Scopus)

抄録

Interconnected pore forming calcium phosphate cement is useful for the reconstruction of bone defects as well as scaffold fabrication in tissue engineering. In this study, interconnected pore forming calcium phosphate cement was fabricated using α-tricalcium phosphate (α-TCP) foam granules. When α-TCP foam granules were mixed with acidic calcium phosphate solution prepared from monocalcium phosphate monohydrate (MCPM) and phosphoric acid solution, brushite crystals were precipitated. These crystals bridged the α-TCP foam granules immediately upon mixing. As a result of the brushite bridge between the α-TCP foam granules, fully interconnected macroporous α-TCP was obtained. The amount of brushite precipitate and the mechanical strength of the set cement increased with acidic calcium phosphate concentration.

本文言語英語
ページ(範囲)838-845
ページ数8
ジャーナルJournal of Biomaterials Applications
30
6
DOI
出版ステータス出版済み - 1 1 2016

All Science Journal Classification (ASJC) codes

  • Biomaterials
  • Biomedical Engineering

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