Fabrication of novel biodegradable particles and application for DDS by self-organized precipitation method

Daisuke Ohsato, Takeshi Higuchi, Hiroshi Yabu, Masaru Tanaka, Sadaaki Yamamoto, Masatsugu Shimomura

研究成果: 会議への寄与タイプ学会誌査読

抄録

Recently, we have reported the formation of nano-particles by mixing a poor solvent into a solution of polymer, and then evaporating a good solvent. In this report, nano-particles were prepared from various biodegradable polymers. Average size of the particles was measured by dynamic light scattering spectrophotometer. The particles were observed by Field-Emission Scanning Electron Microscopy. Uniform sized particles were formed. The particle size was controlled ranging from 100 nm to 1000 nm. In the case of Poly(ε- caprolactone)(PCL), the particle size became larger with increasing the concentration of solution, and increasing the volume ratio of a good solvent / a poor solvent. Fabrication of biodegradable particles containing a drug and the concentration of drug in the particles will be reported.

本文言語英語
ページ4949-4950
ページ数2
出版ステータス出版済み - 12月 1 2005
外部発表はい
イベント54th SPSJ Symposium on Macromolecules - Yamagata, 日本
継続期間: 9月 20 20059月 22 2005

その他

その他54th SPSJ Symposium on Macromolecules
国/地域日本
CityYamagata
Period9/20/059/22/05

!!!All Science Journal Classification (ASJC) codes

  • 工学(全般)

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