Fabrication of ordered arrays of biodegradable polymer pincushions using self-organized honeycomb-patterned films

Masaru Tanaka, Masafumi Takebayashi, Masatsugu Shimomura

研究成果: ジャーナルへの寄稿記事

14 引用 (Scopus)

抄録

Nano- and micropatterned structures of tissue engineering scaffolds made of biodegradable and biocompatible polymers profoundly influence cell behavior. The present study describes a technically simple and inexpensive method to rapidly fabricate hexagonal arrays of biodegradable polymer pillars (pincushions). As precursors to these polymer pincushion arrays, highly regular porous biodegradable polymer films (self-organized honeycomb-patterned films, called honeycomb films) were prepared on a glass substrate using a simple casting technique. Scanning electron microscope observations revealed that the honeycomb film was composed of a top and bottom layer. This double-layered structure is attributable to the self-organization of hexagonally packed arrays of water droplets that form the template. When we peeled off the top layer of the honeycomb film under ambient conditions using adhesive tape, we obtained arrays of polymer pincushions on both side of the glass substrate and on the adhesive tape. Each air hole is surrounded by six pincushions, each with a diameter of 0.1-1 mm. We also studied factors that determine the morphology of the pincushions, such as the thermal and mechanical properties of the polymers used. It was shown that the heights, widths, and distances of separation between the pincushions could be controlled by the choice of polymer and the pore structure of the original honeycomb film. Such well-ordered, biologically inspired pincushion structures could find application in biomedical, photonic, and electronic materials.

元の言語英語
ページ(範囲)175-182
ページ数8
ジャーナルMacromolecular Symposia
279
発行部数1
DOI
出版物ステータス出版済み - 5 1 2009

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Biodegradable polymers
Polymers
Fabrication
fabrication
polymers
Tapes
Adhesives
Tissue Scaffolds
adhesives
tapes
Glass
Substrates
Scaffolds (biology)
Pore structure
Tissue engineering
Polymer films
Photonics
glass
tissue engineering
Casting

All Science Journal Classification (ASJC) codes

  • Condensed Matter Physics
  • Organic Chemistry
  • Polymers and Plastics
  • Materials Chemistry

これを引用

Fabrication of ordered arrays of biodegradable polymer pincushions using self-organized honeycomb-patterned films. / Tanaka, Masaru; Takebayashi, Masafumi; Shimomura, Masatsugu.

:: Macromolecular Symposia, 巻 279, 番号 1, 01.05.2009, p. 175-182.

研究成果: ジャーナルへの寄稿記事

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