Factor B is the second lipopolysaccharide-binding protease zymogen in the horseshoe crab coagulation cascade

Yuki Kobayashi, Toshiaki Takahashi, Toshio Shibata, Shunsuke Ikeda, Takumi Koshiba, Hikaru Mizumura, Toshio Oda, Shun-Ichiro Kawabata

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

抄録

Background: It is not known whether LPS is required for the activation of coagulation factor B. Results: Factor B is an LPS-binding zymogen activated by -factor C in an LPS-dependent manner. Conclusion: The clip domain of factor B has an important role in localizing factor B to LPS. Significance: Horseshoe crab coagulation is an ideal model for understanding proteolytic cascades.

元の言語英語
ページ(範囲)19379-19386
ページ数8
ジャーナルJournal of Biological Chemistry
290
発行部数31
DOI
出版物ステータス出版済み - 7 31 2015

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Horseshoe Crabs
Enzyme Precursors
Complement Factor B
Coagulation
Lipopolysaccharides
Peptide Hydrolases
Blood Coagulation Factors
Surgical Instruments
Chemical activation

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology
  • Cell Biology

これを引用

Factor B is the second lipopolysaccharide-binding protease zymogen in the horseshoe crab coagulation cascade. / Kobayashi, Yuki; Takahashi, Toshiaki; Shibata, Toshio; Ikeda, Shunsuke; Koshiba, Takumi; Mizumura, Hikaru; Oda, Toshio; Kawabata, Shun-Ichiro.

:: Journal of Biological Chemistry, 巻 290, 番号 31, 31.07.2015, p. 19379-19386.

研究成果: ジャーナルへの寄稿記事

Kobayashi, Yuki ; Takahashi, Toshiaki ; Shibata, Toshio ; Ikeda, Shunsuke ; Koshiba, Takumi ; Mizumura, Hikaru ; Oda, Toshio ; Kawabata, Shun-Ichiro. / Factor B is the second lipopolysaccharide-binding protease zymogen in the horseshoe crab coagulation cascade. :: Journal of Biological Chemistry. 2015 ; 巻 290, 番号 31. pp. 19379-19386.
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