Fbxw7 suppresses cancer metastasis by inhibiting niche formation

Kanae Yumimoto, Keiichi I. Nakayama

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)

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Fbxw7 has been identified as an oncosuppressor protein in many types of cancer. We have recently shown that loss of Fbxw7 in bone marrow-derived stromal cells (BMSCs) promotes cancer metastasis by increasing production of the chemokine CCL2, which attracts monocytic myeloid-derived suppressor cells (Mo-MDSCs) and macrophages to the metastatic niche.

元の言語英語
ジャーナルOncoImmunology
4
発行部数8
DOI
出版物ステータス出版済み - 8 3 2015

    フィンガープリント

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology
  • Oncology

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