Feeding behavior in rats fed diets containing medium chain triglyceride

Mitsuhiro Furuse, Yang Ho Choi, Remedios T. Mabayo, Jun Ichi Okumura

研究成果: ジャーナルへの寄稿学術誌査読

47 被引用数 (Scopus)


The effect of dietary medium chain triglyceride (MCT) on shortterm food intake was compared with the effect of long chain triglyceride (LCT) in rats. Corn oil and glyceryl tricaprylate were used as LCT and MCT sources, respectively. Rats were given diets containing 200 g MCT/kg diet (MCT diet), 100 g MCT + 100 g LCT/kg diet (ML diet), or 200 g LCT/kg diet (LCT diet) in Experiment 1. Cumulative food intake was determined every h for the first 12 h, then at 2-h intervals thereafter during the subsequent 12 h. As early as 1 h after feeding, cumulative food intake significantly decreased in MCT-fed animals in a dose-dependent fashion. In Experiment 2, rats were given a choice between MCT and LCT diets for 1 h to confirm whether or not the palatability of diets was influenced by dietary fat sources. There was no difference in food intake between the two diets. In Experiment 3, the responsibility of endogenous cholecytokinin (CCK) for the difference in food intake between the two diets was investigated for 6 h by using a CCK-A receptor antagonist, Devazepide (DVZ, 1 mg/kg b. wt.). Food intake in the MCT diet and also in the LCT diet was improved by DVZ. It is concluded that the satiety, but not the palatability, is affected by carbon chain length in dietary triglyceride sources, although the responsibility of endogenous CCK is very small.

ジャーナルPhysiology and Behavior
出版ステータス出版済み - 10月 1992

!!!All Science Journal Classification (ASJC) codes

  • 実験心理学および認知心理学
  • 行動神経科学


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