Fluctuation of actin sliding over myosin thick filaments in vitro

Naoki Noda, Yasuhiro Imafuku, Akira Yamada, Katsuhisa Tawada

研究成果: 著書/レポートタイプへの貢献会議での発言

抄録

It is customarily assumed that myosin motors act as independent force generators. Here, we tested this assumption by analyzing the fluctuation of the actin sliding movement in vitro over long native thick filaments from shell fish smooth muscle. This analysis is based on the prediction that the effective diffusion coefficient of actin, a measure of the fluctuation, is proportional to the inverse of the number of myosin motors generating the sliding movement of an actin filament, hence proportional to the inverse of the actin length, if the actions of the motors are independent. Contrary to this prediction, we found the effective diffusion coefficient to be independent of the actin length. This result shows that the myosin motors are not independent force generators when generating the continuous sliding movement of actin in vitro.

元の言語英語
ホスト出版物のタイトル2006 IEEE International Symposium on Micro-Nano Mechanical and Human Science, MHS
DOI
出版物ステータス出版済み - 12 1 2006
イベント2006 IEEE International Symposium on Micro-Nano Mechanical and Human Science, MHS - Nagoya, 日本
継続期間: 11 5 200611 8 2006

出版物シリーズ

名前2006 IEEE International Symposium on Micro-Nano Mechanical and Human Science, MHS

その他

その他2006 IEEE International Symposium on Micro-Nano Mechanical and Human Science, MHS
日本
Nagoya
期間11/5/0611/8/06

Fingerprint

fluctuation
Fish
Muscle

All Science Journal Classification (ASJC) codes

  • Computational Mechanics
  • Control and Systems Engineering
  • Human Factors and Ergonomics

これを引用

Noda, N., Imafuku, Y., Yamada, A., & Tawada, K. (2006). Fluctuation of actin sliding over myosin thick filaments in vitro. : 2006 IEEE International Symposium on Micro-Nano Mechanical and Human Science, MHS [4110395] (2006 IEEE International Symposium on Micro-Nano Mechanical and Human Science, MHS). https://doi.org/10.1109/MHS.2006.320292

Fluctuation of actin sliding over myosin thick filaments in vitro. / Noda, Naoki; Imafuku, Yasuhiro; Yamada, Akira; Tawada, Katsuhisa.

2006 IEEE International Symposium on Micro-Nano Mechanical and Human Science, MHS. 2006. 4110395 (2006 IEEE International Symposium on Micro-Nano Mechanical and Human Science, MHS).

研究成果: 著書/レポートタイプへの貢献会議での発言

Noda, N, Imafuku, Y, Yamada, A & Tawada, K 2006, Fluctuation of actin sliding over myosin thick filaments in vitro. : 2006 IEEE International Symposium on Micro-Nano Mechanical and Human Science, MHS., 4110395, 2006 IEEE International Symposium on Micro-Nano Mechanical and Human Science, MHS, 2006 IEEE International Symposium on Micro-Nano Mechanical and Human Science, MHS, Nagoya, 日本, 11/5/06. https://doi.org/10.1109/MHS.2006.320292
Noda N, Imafuku Y, Yamada A, Tawada K. Fluctuation of actin sliding over myosin thick filaments in vitro. : 2006 IEEE International Symposium on Micro-Nano Mechanical and Human Science, MHS. 2006. 4110395. (2006 IEEE International Symposium on Micro-Nano Mechanical and Human Science, MHS). https://doi.org/10.1109/MHS.2006.320292
Noda, Naoki ; Imafuku, Yasuhiro ; Yamada, Akira ; Tawada, Katsuhisa. / Fluctuation of actin sliding over myosin thick filaments in vitro. 2006 IEEE International Symposium on Micro-Nano Mechanical and Human Science, MHS. 2006. (2006 IEEE International Symposium on Micro-Nano Mechanical and Human Science, MHS).
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