Fluorescence detection of metabolic activity of the fatty acid beta oxidation pathway in living cells

Shohei Uchinomiya; Naoya Matsunaga; Koichiro Kamoda; Ryosuke Kawagoe; Akito Tsuruta; Shigehiro Ohdo; Akio Ojida

doi:10.1039/c9cc09993j

Fluorescence detection of metabolic activity of the fatty acid beta oxidation pathway in living cells

Shohei Uchinomiya, Naoya Matsunaga, Koichiro Kamoda, Ryosuke Kawagoe, Akito Tsuruta, Shigehiro Ohdo, Akio Ojida

研究成果: Contribution to journal › Article › 査読

抄録

Detection of metabolic activity in living cells facilitates the understanding of the cell mechanism. Here, we report a fluorescent probe that can detect fatty acid beta oxidation (FAO) in living cells. This probe is metabolically degraded by the sequential enzyme reactions of FAO and can visualize the FAO activity with turn-on fluorescence.

本文言語	英語
ページ（範囲）	3023-3026
ページ数	4
ジャーナル	Chemical Communications
巻	56
号	20
DOI	https://doi.org/10.1039/c9cc09993j
出版ステータス	出版済み - 3 11 2020

All Science Journal Classification (ASJC) codes

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

文献へのアクセス

10.1039/c9cc09993j

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引用スタイル

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abstract = "Detection of metabolic activity in living cells facilitates the understanding of the cell mechanism. Here, we report a fluorescent probe that can detect fatty acid beta oxidation (FAO) in living cells. This probe is metabolically degraded by the sequential enzyme reactions of FAO and can visualize the FAO activity with turn-on fluorescence.",

author = "Shohei Uchinomiya and Naoya Matsunaga and Koichiro Kamoda and Ryosuke Kawagoe and Akito Tsuruta and Shigehiro Ohdo and Akio Ojida",

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AU - Tsuruta, Akito

AU - Ohdo, Shigehiro

AU - Ojida, Akio

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