Fluorescence microscopy data on expression of Paired Box Transcription Factor 7 in skeletal muscle of APOBEC2 knockout mice

Hideaki Ohtsubo, Yusuke Sato, Yuji Matsuyoshi, Takahiro Suzuki, Wataru Mizunoya, Mako Nakamura, Ryuichi Tatsumi, Yoshihide Ikeuchi

研究成果: ジャーナルへの寄稿記事

抄録

The data presented in this article are related to the research articles entitled “APOBEC2 negatively regulates myoblast differentiation in muscle regeneration” and “Data supporting possible implication of APOBEC2 in self-renewal functions of myogenic stem satellite cells: toward understanding the negative regulation of myoblast differentiation” (Ohtsubo et al., 2017a, 2017b) [1,2]. This article provides in vivo phenotypical data to show that Paired Box Transcription Factor 7 (Pax7)-positive cell number (per myofiber) is significantly lower in APOBEC2 (a member of apoB mRNA editing enzyme, catalytic polypeptide-like family)-knockout muscle than the control wild-type tissue at the same age of 8-wk-old in mice. The emerging results support an essential role for APOBEC2 in the self-renewal functions of myogenic stem satellite cells, namely the re-establishment of quiescent status after activation and proliferation of myoblasts.

元の言語英語
ページ(範囲)1348-1351
ページ数4
ジャーナルData in Brief
17
DOI
出版物ステータス出版済み - 4 1 2018

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PAX7 Transcription Factor
Myoblasts
Skeletal Muscle Satellite Cells
Fluorescence Microscopy
Knockout Mice
Skeletal Muscle
Stem Cells
Muscles
Apolipoproteins B
Regeneration
Cell Count
Messenger RNA
Peptides
Enzymes
Research

All Science Journal Classification (ASJC) codes

  • General

これを引用

Fluorescence microscopy data on expression of Paired Box Transcription Factor 7 in skeletal muscle of APOBEC2 knockout mice. / Ohtsubo, Hideaki; Sato, Yusuke; Matsuyoshi, Yuji; Suzuki, Takahiro; Mizunoya, Wataru; Nakamura, Mako; Tatsumi, Ryuichi; Ikeuchi, Yoshihide.

:: Data in Brief, 巻 17, 01.04.2018, p. 1348-1351.

研究成果: ジャーナルへの寄稿記事

Ohtsubo, Hideaki ; Sato, Yusuke ; Matsuyoshi, Yuji ; Suzuki, Takahiro ; Mizunoya, Wataru ; Nakamura, Mako ; Tatsumi, Ryuichi ; Ikeuchi, Yoshihide. / Fluorescence microscopy data on expression of Paired Box Transcription Factor 7 in skeletal muscle of APOBEC2 knockout mice. :: Data in Brief. 2018 ; 巻 17. pp. 1348-1351.
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AU - Mizunoya, Wataru

AU - Nakamura, Mako

AU - Tatsumi, Ryuichi

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