Fluoridation of hydroxyapatite powder by ammonium hexafluorosilicate

H. Murata, K. Ishikawa, S. Tenshin, S. Horiuchi, M. Nakanishi, K. Asaoka, T. Kawata, T. T. Yamamoto

研究成果: Contribution to journalArticle査読

19 被引用数 (Scopus)


Diamine silver fluoride [AgF: (NH3)2AgF] is a unique fluoride solution used clinically in Japan for primary teeth. AgF has been shown to reduce dental caries and dentine hypersensitivity. However, AgF also stains teeth black due to sulfide precipitation and thus is unacceptable for permanent teeth. In the present study, the potential value of ammonium hexafluorosilicate [SiF: (NH4)2SiF6], which has a formula similar to that of AgF but contains no Ag, was studied with respect to its ability to fluoridate apatite. Hydroxyapatite [HAP: Ca10(PO4)6(OH)2] powder was treated with several topical fluoride solutions, i.e. neutral sodium fluoride, acidulated phosphate fluoride (APF) along with AgF and SiF. Following treatment, the HAP powders were analyzed for their fluorine content, crystal -linity changes, and solubility in acidic solution. The highest level of fluoridated HAP [FAP: Ca10(PO4)6(OH)xF2––x] was observed in HAP powder treated with SiF, even though more total fluorine in the form of FAP and CaF2 was observed in HAP powder samples treated with APF. Presumably as a consequence of this higher level of FAP formation after SiF treatment, the highest level of crystallinity along with the lowest solubility in acidic solution were observed in HAP powder treated with SiF solution. We concluded, therefore, that SiF may have potential value for use as a topical fluoride solution.

ジャーナルCaries Research
出版ステータス出版済み - 1 1 1996

All Science Journal Classification (ASJC) codes

  • Dentistry(all)

フィンガープリント 「Fluoridation of hydroxyapatite powder by ammonium hexafluorosilicate」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。