Follicular pancreatitis, report of a case clinically mimicking pancreatic cancer and literature review

Yusuke Mizuuchi, Shinichi Aishima, Masami Hattori, Yasuhiro Ushijima, Akira Aso, Shunichi Takahata, Takao Ohtsuka, Junji Ueda, Masao Tanaka, Yoshinao Oda

研究成果: ジャーナルへの寄稿記事

7 引用 (Scopus)

抄録

We herein present a 71-year-old man who underwent pancreatoduodenectomy with the diagnosis of follicular pancreatitis. We could not completely deny malignancy by a preoperative imaging study. Endoscopic ultrasonography-guided fine needle aspiration biopsy demonstrated clusters of benign acinar cells and no proliferation of atypical lymphoid cells or rich plasma cells. Histologically, the prominent lymphoid follicle formation was seen in an ill-defined mass, 15. mm in size, in the pancreatic parenchyma. Duct-centered fibrotic rims were seen in the pancreatic ducts accompanied by mild fibrotic change between the follicles and obliterative phlebitis. No neoplastic epithelial cells were observed in the resected specimen, and infiltrating lymphocytes did not show any morphological atypia and monoclonal proliferation by immunohistochemical staining with B and T cell markers. In addition, we could exclude IgG4-related disease, because plasmacytic cells were rarely positive for IgG4. Although follicular pancreatitis is rare, this mass-forming inflammatory disease (pancreatitis) should be included in the preoperative differential diagnosis of pancreatic cancer.

元の言語英語
ページ(範囲)118-122
ページ数5
ジャーナルPathology Research and Practice
210
発行部数2
DOI
出版物ステータス出版済み - 2 1 2014

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Pancreatic Neoplasms
Pancreatitis
Immunoglobulin G
Lymphocytes
Phlebitis
Endosonography
Pancreaticoduodenectomy
Acinar Cells
Pancreatic Ducts
Fine Needle Biopsy
Plasma Cells
Differential Diagnosis
B-Lymphocytes
Epithelial Cells
Cell Proliferation
Staining and Labeling
T-Lymphocytes
Neoplasms

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Cell Biology

これを引用

Follicular pancreatitis, report of a case clinically mimicking pancreatic cancer and literature review. / Mizuuchi, Yusuke; Aishima, Shinichi; Hattori, Masami; Ushijima, Yasuhiro; Aso, Akira; Takahata, Shunichi; Ohtsuka, Takao; Ueda, Junji; Tanaka, Masao; Oda, Yoshinao.

:: Pathology Research and Practice, 巻 210, 番号 2, 01.02.2014, p. 118-122.

研究成果: ジャーナルへの寄稿記事

Mizuuchi, Yusuke ; Aishima, Shinichi ; Hattori, Masami ; Ushijima, Yasuhiro ; Aso, Akira ; Takahata, Shunichi ; Ohtsuka, Takao ; Ueda, Junji ; Tanaka, Masao ; Oda, Yoshinao. / Follicular pancreatitis, report of a case clinically mimicking pancreatic cancer and literature review. :: Pathology Research and Practice. 2014 ; 巻 210, 番号 2. pp. 118-122.
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