Foveal and Macular Thickness in a Japanese Population: The Hisayama Study

Sawako Hashimoto, Miho Yasuda, Toshiharu Ninomiya, Jun Hata, Daigo Yoshida, Tomoko Tahara-Asakuma, Yoichiro Hirakawa, Satoshi Arakawa, Kota Fujiwara, Yutaka Kiyohara, Tatsuro Ishibashi

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

抄録

Purpose: To examine factors associated with foveal thickness (FT) and macular thickness (MT) in Japanese persons from Hisayama. Methods: A total of 2216 healthy eyes of 1384 participants were analyzed. Each participant underwent comprehensive physical and ophthalmic examinations, the latter including optical coherence tomography (OCT). Multiple regression analysis was used to determine the relationship of various factors (race, age, sex, refractive error, axial length, diabetes mellitus, fasting plasma glucose levels, alcohol intake and smoking status) to FT (central 1-mm foveal area) and MT (central 3-mm foveal region). Results: Results of multiple linear regression analysis indicated that age was positively associated with FT (β coefficient 0.214 μm). FT was significantly smaller in women than men (β coefficient −9.146 μm). For both sexes, body height was positively correlated (β coefficient 0.257 μm), while refractive error and current smoking were negatively associated (β coefficients −1910 μm and −4.410 μm, respectively) with FT. With respect to MT, there were negative associations between age, sex (female), and refractive error (β coefficients −0.268 μm, −4.815 μm and −0.699 μm, respectively). For both sexes, body height was positively correlated (β coefficient 0.227 μm), while hypertension and current smoking were negatively associated (β coefficients −1.999 μm and −2.758 μm, respectively) with MT. Conclusions: Our results indicated that age, body height, refractive error, and current smoking were significantly associated with FT, whereas age, body height, refractive error, current smoking, and hypertension were significantly related to MT. Women had significantly smaller FT and MT than men.

元の言語英語
ページ(範囲)202-208
ページ数7
ジャーナルOphthalmic Epidemiology
23
発行部数3
DOI
出版物ステータス出版済み - 5 3 2016

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Refractive Errors
Body Height
Smoking
Population
Regression Analysis
Hypertension
Age Factors
Optical Coherence Tomography
Physical Examination
Linear Models
Fasting
Diabetes Mellitus
Alcohols
Glucose

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Ophthalmology

これを引用

Foveal and Macular Thickness in a Japanese Population : The Hisayama Study. / Hashimoto, Sawako; Yasuda, Miho; Ninomiya, Toshiharu; Hata, Jun; Yoshida, Daigo; Tahara-Asakuma, Tomoko; Hirakawa, Yoichiro; Arakawa, Satoshi; Fujiwara, Kota; Kiyohara, Yutaka; Ishibashi, Tatsuro.

:: Ophthalmic Epidemiology, 巻 23, 番号 3, 03.05.2016, p. 202-208.

研究成果: ジャーナルへの寄稿記事

Hashimoto, Sawako ; Yasuda, Miho ; Ninomiya, Toshiharu ; Hata, Jun ; Yoshida, Daigo ; Tahara-Asakuma, Tomoko ; Hirakawa, Yoichiro ; Arakawa, Satoshi ; Fujiwara, Kota ; Kiyohara, Yutaka ; Ishibashi, Tatsuro. / Foveal and Macular Thickness in a Japanese Population : The Hisayama Study. :: Ophthalmic Epidemiology. 2016 ; 巻 23, 番号 3. pp. 202-208.
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abstract = "Purpose: To examine factors associated with foveal thickness (FT) and macular thickness (MT) in Japanese persons from Hisayama. Methods: A total of 2216 healthy eyes of 1384 participants were analyzed. Each participant underwent comprehensive physical and ophthalmic examinations, the latter including optical coherence tomography (OCT). Multiple regression analysis was used to determine the relationship of various factors (race, age, sex, refractive error, axial length, diabetes mellitus, fasting plasma glucose levels, alcohol intake and smoking status) to FT (central 1-mm foveal area) and MT (central 3-mm foveal region). Results: Results of multiple linear regression analysis indicated that age was positively associated with FT (β coefficient 0.214 μm). FT was significantly smaller in women than men (β coefficient −9.146 μm). For both sexes, body height was positively correlated (β coefficient 0.257 μm), while refractive error and current smoking were negatively associated (β coefficients −1910 μm and −4.410 μm, respectively) with FT. With respect to MT, there were negative associations between age, sex (female), and refractive error (β coefficients −0.268 μm, −4.815 μm and −0.699 μm, respectively). For both sexes, body height was positively correlated (β coefficient 0.227 μm), while hypertension and current smoking were negatively associated (β coefficients −1.999 μm and −2.758 μm, respectively) with MT. Conclusions: Our results indicated that age, body height, refractive error, and current smoking were significantly associated with FT, whereas age, body height, refractive error, current smoking, and hypertension were significantly related to MT. Women had significantly smaller FT and MT than men.",
author = "Sawako Hashimoto and Miho Yasuda and Toshiharu Ninomiya and Jun Hata and Daigo Yoshida and Tomoko Tahara-Asakuma and Yoichiro Hirakawa and Satoshi Arakawa and Kota Fujiwara and Yutaka Kiyohara and Tatsuro Ishibashi",
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T1 - Foveal and Macular Thickness in a Japanese Population

T2 - The Hisayama Study

AU - Hashimoto, Sawako

AU - Yasuda, Miho

AU - Ninomiya, Toshiharu

AU - Hata, Jun

AU - Yoshida, Daigo

AU - Tahara-Asakuma, Tomoko

AU - Hirakawa, Yoichiro

AU - Arakawa, Satoshi

AU - Fujiwara, Kota

AU - Kiyohara, Yutaka

AU - Ishibashi, Tatsuro

PY - 2016/5/3

Y1 - 2016/5/3

N2 - Purpose: To examine factors associated with foveal thickness (FT) and macular thickness (MT) in Japanese persons from Hisayama. Methods: A total of 2216 healthy eyes of 1384 participants were analyzed. Each participant underwent comprehensive physical and ophthalmic examinations, the latter including optical coherence tomography (OCT). Multiple regression analysis was used to determine the relationship of various factors (race, age, sex, refractive error, axial length, diabetes mellitus, fasting plasma glucose levels, alcohol intake and smoking status) to FT (central 1-mm foveal area) and MT (central 3-mm foveal region). Results: Results of multiple linear regression analysis indicated that age was positively associated with FT (β coefficient 0.214 μm). FT was significantly smaller in women than men (β coefficient −9.146 μm). For both sexes, body height was positively correlated (β coefficient 0.257 μm), while refractive error and current smoking were negatively associated (β coefficients −1910 μm and −4.410 μm, respectively) with FT. With respect to MT, there were negative associations between age, sex (female), and refractive error (β coefficients −0.268 μm, −4.815 μm and −0.699 μm, respectively). For both sexes, body height was positively correlated (β coefficient 0.227 μm), while hypertension and current smoking were negatively associated (β coefficients −1.999 μm and −2.758 μm, respectively) with MT. Conclusions: Our results indicated that age, body height, refractive error, and current smoking were significantly associated with FT, whereas age, body height, refractive error, current smoking, and hypertension were significantly related to MT. Women had significantly smaller FT and MT than men.

AB - Purpose: To examine factors associated with foveal thickness (FT) and macular thickness (MT) in Japanese persons from Hisayama. Methods: A total of 2216 healthy eyes of 1384 participants were analyzed. Each participant underwent comprehensive physical and ophthalmic examinations, the latter including optical coherence tomography (OCT). Multiple regression analysis was used to determine the relationship of various factors (race, age, sex, refractive error, axial length, diabetes mellitus, fasting plasma glucose levels, alcohol intake and smoking status) to FT (central 1-mm foveal area) and MT (central 3-mm foveal region). Results: Results of multiple linear regression analysis indicated that age was positively associated with FT (β coefficient 0.214 μm). FT was significantly smaller in women than men (β coefficient −9.146 μm). For both sexes, body height was positively correlated (β coefficient 0.257 μm), while refractive error and current smoking were negatively associated (β coefficients −1910 μm and −4.410 μm, respectively) with FT. With respect to MT, there were negative associations between age, sex (female), and refractive error (β coefficients −0.268 μm, −4.815 μm and −0.699 μm, respectively). For both sexes, body height was positively correlated (β coefficient 0.227 μm), while hypertension and current smoking were negatively associated (β coefficients −1.999 μm and −2.758 μm, respectively) with MT. Conclusions: Our results indicated that age, body height, refractive error, and current smoking were significantly associated with FT, whereas age, body height, refractive error, current smoking, and hypertension were significantly related to MT. Women had significantly smaller FT and MT than men.

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