Function and expression of transcription factors implicated in gonadal differentiation

研究成果: Contribution to journalReview article査読

抄録

Several transcription factors such as SRY, DAX-1, Ad4BP/SF-1, WT-1 and SOX -9, have been revealed to be implicated in gonadal development by analyzing the genetic disorders of human and the gene disrupted mice. All of these transcription factors are expressed in the early stage of the gonadal development and the expression profiles during the gonadal development are clearly different between the two sexes. Functions of the transcription factors are discussed by referring genes under the control of these factors. Effects of endocrine disruptants on the expression of Ad4BP/SF-1 in the fetal gonads was also discussed.

本文言語英語
ページ(範囲)1739-1744
ページ数6
ジャーナルNippon rinsho. Japanese journal of clinical medicine
56
7
出版ステータス出版済み - 7 1998
外部発表はい

All Science Journal Classification (ASJC) codes

  • 医学(全般)

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