Functional controlled release systems triggered by photothermal effect of gold nanorods

Shuji Yamashita, Hiromitsu Fukushima, Yasuro Niidome, Takeshi Mori, Yoshiki Katayama, Takuro Niidome

    研究成果: Chapter in Book/Report/Conference proceedingConference contribution

    抄録

    Gold nanorods, rod-shaped gold nanoparticles, have transverse and longitudinal surface plasmon (SP) bands at visible and near-infrared (IR) regions, respectively. Since the absorbed light energy is converted into heat, photothermal effect of gold nanorods can be triggered without damaging the tissues in the path of near-IR laser light. In this study, we tried to construct controlled release system of functional molecules from surface of gold nanorods mediated by the photothermal effect. First, we evaluated controlled release of poly(ethyleneglycol) (PEG) chains from PEG-modified gold nanorods (PEG-NR). Next, we employed double stranded oligonucleotide as a thermo-responsive dissociating group (DNA-NR). Finally, we evaluated photothermal release of PEG chains mediated retro-Diels-Alder reaction (PEG-DA-NR). For construction of controlled release system of functional molecules, these studies will provide important information about the photothermal reactions of surface molecules on the gold nanorods triggered by near-IR light irradiation.

    本文言語英語
    ホスト出版物のタイトルBiological Imaging and Sensing Using Nanoparticle Assemblies
    ページ27-32
    ページ数6
    出版ステータス出版済み - 10 15 2010
    イベント2009 MRS Fall Meeting - Boston, MA, 米国
    継続期間: 11 30 200912 4 2009

    出版物シリーズ

    名前Materials Research Society Symposium Proceedings
    1241
    ISSN(印刷版)0272-9172

    その他

    その他2009 MRS Fall Meeting
    国/地域米国
    CityBoston, MA
    Period11/30/0912/4/09

    All Science Journal Classification (ASJC) codes

    • 材料科学(全般)
    • 凝縮系物理学
    • 材料力学
    • 機械工学

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