Functionalized hydrogel surface patterned in a chip for local PH sensing

H. Maruyama, Hiroshige Matsumoto, T. Fukuda, F. Arai

研究成果: 著書/レポートタイプへの貢献会議での発言

9 引用 (Scopus)

抄録

We developed a novel technique to investigate local pH distribution on a chip using patterned hydrogel film made of UV photosensitive resin. The hydrogel is first patterned by photolithography in any shape on a glass, and later functionalized with the pH indicator, for example, Bromocresol Green (BCG). The hydrogel is polymerized by UV-ray illumination (300-400 nm) on the glass substrate, which is spin coated with the water-soluble prepolymer solution, and immobilized on the glass surface. Unexposed part can be removed easily by water. The hydrogel is hydrophilic, transparent, biocompatible, and is impregnated with the BCG. Then, the Polydimethylsiloxane (PDMS) microchannel is assembled and bonded on the functionalize surface. In this way, we can make patterned pH sensitive surface in the microchannel. Local pH is measured from the color of the hydrogel impregnated with BCG based on the calibrated color information in YCrCb color space. We succeeded in measuring local pH distribution in the microchip.

元の言語英語
ホスト出版物のタイトルMEMS 2008 Tucson - 21st IEEE International Conference on Micro Electro Mechanical Systems
ページ224-227
ページ数4
DOI
出版物ステータス出版済み - 2008
外部発表Yes
イベント21st IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2008 Tucson - Tucson, AZ, 米国
継続期間: 1 13 20081 17 2008

その他

その他21st IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2008 Tucson
米国
Tucson, AZ
期間1/13/081/17/08

Fingerprint

Bromcresol Green
Hydrogel
Hydrogels
chips
Microchannels
Color
Glass
microchannels
color
glass
Water
prepolymers
Photolithography
Polydimethylsiloxane
photolithography
Resins
Lighting
resins
water
rays

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

これを引用

Maruyama, H., Matsumoto, H., Fukuda, T., & Arai, F. (2008). Functionalized hydrogel surface patterned in a chip for local PH sensing. : MEMS 2008 Tucson - 21st IEEE International Conference on Micro Electro Mechanical Systems (pp. 224-227). [4443633] https://doi.org/10.1109/MEMSYS.2008.4443633

Functionalized hydrogel surface patterned in a chip for local PH sensing. / Maruyama, H.; Matsumoto, Hiroshige; Fukuda, T.; Arai, F.

MEMS 2008 Tucson - 21st IEEE International Conference on Micro Electro Mechanical Systems. 2008. p. 224-227 4443633.

研究成果: 著書/レポートタイプへの貢献会議での発言

Maruyama, H, Matsumoto, H, Fukuda, T & Arai, F 2008, Functionalized hydrogel surface patterned in a chip for local PH sensing. : MEMS 2008 Tucson - 21st IEEE International Conference on Micro Electro Mechanical Systems., 4443633, pp. 224-227, 21st IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2008 Tucson, Tucson, AZ, 米国, 1/13/08. https://doi.org/10.1109/MEMSYS.2008.4443633
Maruyama H, Matsumoto H, Fukuda T, Arai F. Functionalized hydrogel surface patterned in a chip for local PH sensing. : MEMS 2008 Tucson - 21st IEEE International Conference on Micro Electro Mechanical Systems. 2008. p. 224-227. 4443633 https://doi.org/10.1109/MEMSYS.2008.4443633
Maruyama, H. ; Matsumoto, Hiroshige ; Fukuda, T. ; Arai, F. / Functionalized hydrogel surface patterned in a chip for local PH sensing. MEMS 2008 Tucson - 21st IEEE International Conference on Micro Electro Mechanical Systems. 2008. pp. 224-227
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