TY - JOUR
T1 - Gastric cancer during pregnancy with placental involvement
T2 - Case report and review of published works
AU - Oga, Seiya
AU - Hachisuga, Masahiro
AU - Hidaka, Nobuhiro
AU - Fujita, Yasuyuki
AU - Tomonobe, Hiroshi
AU - Yamamoto, Hidetaka
AU - Kato, Kiyoko
N1 - Publisher Copyright:
© 2019 Korean Society of Obstetrics and Gynecology.
PY - 2019/9/1
Y1 - 2019/9/1
N2 - Gastric cancer involving the placenta during pregnancy is rare; however, we present 1 such case in this report. A 31-year-old Japanese woman was referred at 26 weeks of gestation for the evaluation of a swollen left supraclavicular lymph node. Biopsy revealed poorly differentiated adenocarcinoma, and esophagogastroduodenoscopy with biopsy of the stomach confirmed the diagnosis of gastric cancer. Her epigastric and back pain became more pronounced and her general status worsened, and we performed a cesarean delivery at 29 weeks. Microscopic examination of the placental specimen revealed poorly differentiated adenocarcinoma cells diffused into the intervillous space. Postpartum chemotherapy consisted of S-1 plus oxaliplatin. Unfortunately, this treatment was ineffective, and the patient died 3 months after delivery. The infant did well, without clinical or laboratory manifestations of metastasis. In patients with advanced gastric cancer during pregnancy, it is important to perform a microscopic examination of the placenta to evaluate for metastatic involvement.
AB - Gastric cancer involving the placenta during pregnancy is rare; however, we present 1 such case in this report. A 31-year-old Japanese woman was referred at 26 weeks of gestation for the evaluation of a swollen left supraclavicular lymph node. Biopsy revealed poorly differentiated adenocarcinoma, and esophagogastroduodenoscopy with biopsy of the stomach confirmed the diagnosis of gastric cancer. Her epigastric and back pain became more pronounced and her general status worsened, and we performed a cesarean delivery at 29 weeks. Microscopic examination of the placental specimen revealed poorly differentiated adenocarcinoma cells diffused into the intervillous space. Postpartum chemotherapy consisted of S-1 plus oxaliplatin. Unfortunately, this treatment was ineffective, and the patient died 3 months after delivery. The infant did well, without clinical or laboratory manifestations of metastasis. In patients with advanced gastric cancer during pregnancy, it is important to perform a microscopic examination of the placenta to evaluate for metastatic involvement.
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U2 - 10.5468/ogs.2019.62.5.357
DO - 10.5468/ogs.2019.62.5.357
M3 - Article
AN - SCOPUS:85072563757
VL - 62
SP - 357
EP - 361
JO - Obstetrics and Gynecology Science
JF - Obstetrics and Gynecology Science
SN - 2287-8572
IS - 5
ER -